138380-14-0

Basic information

• Product Name: Silane, (chloromethyl)methylbis(phenylmethoxy)-
• CAS NO: 138380-14-0
• Molecular Formula: C16H19ClO2Si
• Molecular Weight: 306.864
• Mol File: 138380-14-0.mol

Chemical Properties

• CAS DataBase Reference: Silane, (chloromethyl)methylbis(phenylmethoxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: Silane, (chloromethyl)methylbis(phenylmethoxy)-(138380-14-0)
• EPA Substance Registry System: Silane, (chloromethyl)methylbis(phenylmethoxy)-(138380-14-0)

Safety Data

• Hazardous Substances Data: 138380-14-0(Hazardous Substances Data)

Upstream product

• 100-51-6 benzyl alcohol 
• 1558-33-4 chloromethylmethyldichlorosilane 

Downstream Products

• 138380-29-7 1-(Benzyloxymethyl-tert-butyl-methyl-silanyl)-1-phenyl-ethanol 
• 138380-25-3 <(benzyloxy)methyl>(tert-butyl)(1-ethoxyethenyl)methylsilane 
• 138380-12-8 <<(benzyloxy)methyl>(tert-butyl)methylsilyl> methyl ketone 
• 138380-32-2 1-(Benzyloxymethyl-tert-butyl-methyl-silanyl)-ethanol 
• 138380-22-0 <(benzyloxy)methyl>(tert-butyl)(chloro)methylsilane 
• 138380-19-5 <(benzyloxy)methyl>(tert-butyl)methylsilane 
• 61214-13-9 methyltris(benzyloxy)silane 
• 138380-16-2 bis(benzyloxy)<(benzyloxy)methyl>methylsilane 

Relevant articles and documents

Chiral Acylsilanes in Organic Synthesis. Diastereoselective 1,2 Additions to Racemic Alkoxymethyl-Substituted Acylsilanes

The synthesis of the three alkoxymethyl-sustituted acylsilanes 1-3 is described (Schemes 1 and 2).Their reactions with NaBH4 as well as PhLi gave the corresponding alcohols with moderate to good diastereoisomeric induction (up to 78percent de; see Table), depending upon the solvent used (Scheme 3).The results indicate that in Et2O, the reactions with PhLi proceed via 6-membered chelates (see C in Scheme 4) leading to the products with high de's (74 - 78percent).In THF, these chelates are not formed, and as a consequence, the additions take place with reversed and lower stereoselectivities (34 - 50percent de).