138386-93-3Relevant academic research and scientific papers
Domino N2-Extrusion-Cyclization of Alkynylarylketone Derivatives for the Synthesis of Indoloquinolines and Carbocycle-Fused Quinolines
Akkachairin, Bhornrawin,Tummatorn, Jumreang,Khamsuwan, Narumol,Thongsornkleeb, Charnsak,Ruchirawat, Somsak
, p. 11254 - 11268 (2018)
New synthetic approaches for the synthesis of indoloquinolines and carbocycle-fused quinolines have been developed employing alkynylketone substrates. These synthetic transformations involved the application of N2-extrusion of azido complexes as a key step to generate carbodiimidium ion and nitrilium ion in situ, which further cyclized intramolecularly with alkyne via a domino process to provide indoloquinolines and carbocycle-fused quinolines, respectively, in moderate to good yields.
Microwave-Assisted Cascade Strategy for the Synthesis of Indolo[2,3-b]quinolines from 2-(Phenylethynyl)anilines and Aryl Isothiocynates
Ali, Wajid,Dahiya, Anjali,Pandey, Ramdhari,Alam, Tipu,Patel, Bhisma K.
, p. 2089 - 2096 (2017/02/26)
The in situ generated o-alkynylthioureas obtain by reacting 2-(phenylethynyl)anilines and aryl isothiocynates undergo efficient cascade cyclization in the presence of Ag2CO3 to form indoloquinolines under microwave heating. The prese
