138395-73-0Relevant articles and documents
Asymmetric desymmetrization of meso-cyclopentitol using a C2-symmetric bis-sulfoxide: A synthesis of (-)-allosamizoline
Maezaki, Naoyoshi,Sakamoto, Atsunobu,Tanaka, Tetsuaki,Iwata, Chuzo
, p. 179 - 182 (2007/10/03)
A synthesis of (-)-allosamizoline was accomplished via asymmetric desymmetrization of a meso-cyclopentitol using the C2-symmetric bis-sulfoxide 5 as a chiral auxiliary.
Synthesis of (-)-Allosamizoline, the Pseudoaminosugar Moiety of Allosamidin, a Chitinase Inhibitor
Kitahara, Takeshi,Suzuki, Norio,Koseki, Koshi,Mori, Kenji
, p. 1906 - 1909 (2007/10/02)
The enantioselective synthesis of (-)-allosamizoline (2a), the aminocyclitol moiety of allosamidin (1a), was achieved by starting from D-glucosamine (3).Intramolecular nitrile oxide cycloaddition was adopted as the key step to construct a functional cyclo
An Enantiospecific Synthesis of Allosamizoline
Simpkins, Nigel S.,Stokes, Stephen,Whittle, Alan J.
, p. 2471 - 2478 (2007/10/02)
An enantiospecific synthesis of allosamizoline 4, the aglycone of the chitinase inhibitor allosamidin 3, has been achieved, starting from readily available glucosamine.The key step in the synthesis involves the cyclisation of a carbon-centred radical onto