138395-78-5

Basic information

• Product Name: 2H-Cyclopentoxazol-2-one, hexahydro-4,5-dihydroxy-6-(hydroxymethyl)-, 3aR-(3a.alpha.,4.alpha.,5.beta.,6.alpha.,6a.alpha.)-
• Synonyms: 2H-Cyclopentoxazol-2-one, hexahydro-4,5-dihydroxy-6-(hydroxymethyl)-, 3aR-(3a.alpha.,4.alpha.,5.beta.,6.alpha.,6a.alpha.)-
• CAS NO: 138395-78-5
• Molecular Weight: 0
• Mol File: 138395-78-5.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2H-Cyclopentoxazol-2-one, hexahydro-4,5-dihydroxy-6-(hydroxymethyl)-, 3aR-(3a.alpha.,4.alpha.,5.beta.,6.alpha.,6a.alpha.)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-Cyclopentoxazol-2-one, hexahydro-4,5-dihydroxy-6-(hydroxymethyl)-, 3aR-(3a.alpha.,4.alpha.,5.beta.,6.alpha.,6a.alpha.)-(138395-78-5)
• EPA Substance Registry System: 2H-Cyclopentoxazol-2-one, hexahydro-4,5-dihydroxy-6-(hydroxymethyl)-, 3aR-(3a.alpha.,4.alpha.,5.beta.,6.alpha.,6a.alpha.)-(138395-78-5)

Safety Data

• Hazardous Substances Data: 138395-78-5(Hazardous Substances Data)

Upstream product

• 138395-63-8 2-((3R,4R,5S,6S)-4,5-Dihydroxy-6-iodomethyl-2-methoxy-tetrahydro-pyran-3-yl)-isoindole-1,3-dione 
• 138395-67-2 (2R,3R,4R)-3,4-Bis-(tert-butyl-dimethyl-silanyloxy)-2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-hex-5-enal 
• 138395-65-0 2-[(1R,2R,3R)-1-(Bis-ethylsulfanyl-methyl)-2,3-dihydroxy-pent-4-enyl]-isoindole-1,3-dione 
• 76101-14-9 2-((3R,4R,5S,6R)-4,5-Dihydroxy-6-hydroxymethyl-2-methoxy-tetrahydro-pyran-3-yl)-isoindole-1,3-dione 
• 138395-75-2 (1S,2S,3R,4R,5S)-2-Amino-3,4-bis-(tert-butyl-dimethyl-silanyloxy)-5-hydroxymethyl-cyclopentanol 
• 10022-13-6 1,3,4,6-tetra-O-acetyl-2-deoxy-2-phthalimido-D-glucopyranose 
• 80675-64-5 (3R,4R,5R)-3,4-dibenzoyloxy-5-(hydroxymethyl)cyclopent-1-ene 
• 204448-92-0 (1R,2R,3R,4S,5S)-2,3,5-Tris-benzyloxy-4-benzyloxymethyl-cyclopentanol 
• 204448-93-1 C₃₄H₃₅N₃O₄ 
• 204448-89-5 (1S,2R,3R,4S,5S)-3,5-Bis-benzyloxy-4-benzyloxymethyl-cyclopentane-1,2-diol 
• 100021-11-2 (1α,2β,3α)-2-(benzyloxymethyl)cyclopent-4-ene-1,3-diol 
• 165375-20-2 (1R,2R,3S,4S,5S)-3-(ethoxycarbonylamino)-4-hydroxy-5-(hydroxymethyl)cyclo-pentane-1,2-diyl dibenzoate 
• 138395-72-9 2-aza-7,8-di-t-butyldimethylsiloxy-6-hydroxymethyl-4-oxabicyclo<3.3.0>octan-3-one 
• 138395-66-1 2-[(1R,2R,3R)-1-(Bis-ethylsulfanyl-methyl)-2,3-bis-(tert-butyl-dimethyl-silanyloxy)-pent-4-enyl]-isoindole-1,3-dione 

Downstream Products

• 114673-96-0 (-)-allosamizoline hydrochloride 
• 103766-13-8 (1S,5R)-3-dimethylamino-6-exo-7-endo-dihydroxy-8-exo-hydroxymethyl-2-oxa-4-azabicyclo<3.3.0>oct-3-ene 
• 114621-71-5 3,4,6-tri-O-acetylallosamizoline 
• 138395-73-0 (3aS,4R,5R,6S,6aS)-6-(Acetoxymethyl)-2-oxohexahydro-2H-cyclopenta[d]oxazole-4,5-diyl diacetate 

Relevant articles and documents

Asymmetric desymmetrization of meso-cyclopentitol using a C2-symmetric bis-sulfoxide: A synthesis of (-)-allosamizoline

A synthesis of (-)-allosamizoline was accomplished via asymmetric desymmetrization of a meso-cyclopentitol using the C2-symmetric bis-sulfoxide 5 as a chiral auxiliary.

Enantiospecific total synthesis of (-)-allosamizoline, and aminocyclitol moiety of the insect chitinase inhibitor allosamidin

Total synthesis of (-)-allosamizoline (2), an aminocyclitol moiety of the insect chitinase inhibitor allosamidin (1) has been enantiospecifically synthesized from D-glucosamine by using an intramolecular cycloaddition of the nitrile oxide to an olefin as a key step.