138402-13-8

Usage

Uses

Used in Medicinal Chemistry:
4-[(benzyloxy)carbonyl]aminotetrahydro-2H-pyran-4-carboxylic acid is used as a building block for the synthesis of various pharmaceutical compounds due to its unique structure and functional groups. Its presence in drug molecules can potentially enhance their biological activity and pharmacological properties.
Used in Drug Discovery:
In the field of drug discovery, 4-[(benzyloxy)carbonyl]aminotetrahydro-2H-pyran-4-carboxylic acid is used as a starting material for the development of new drugs. Its complex molecular structure allows for the exploration of its potential interactions with biological targets, which can lead to the discovery of novel therapeutic agents.
Used in Pharmaceutical Industries:
4-[(benzyloxy)carbonyl]aminotetrahydro-2H-pyran-4-carboxylic acid is used as an intermediate in the production of pharmaceuticals. Its unique structure and functional groups can be utilized in the synthesis of active pharmaceutical ingredients, contributing to the development of new and effective medications.
Further research and analysis are required to fully understand the properties and potential uses of this chemical compound, as its complex structure and functional groups may offer a wide range of applications in various industries.

Upstream product

• 39124-19-1 8-oxa-1,3-diazaspiro[4.5]decane-2,4-dione 
• 501-53-1 benzyl chloroformate 
• 39124-20-4 4-aminotetrahydro-2H-pyran-4-carboxylic acid 
• 29943-42-8 Tetrahydro-4H-pyran-4-one 
• 13139-17-8 N-(Benzyloxycarbonyloxy)succinimide 
• 101-83-7 N-cyclohexyl-cyclohexanamine 
• 1379328-03-6 C₆H₁₀NO₃^(1-)*K⁽¹⁺⁾ 

Downstream Products

• 951401-15-3 (4-isobutylcarbamoyl-tetrahydro-pyran-4-yl)-carbamic acid benzyl ester 
• 1367370-17-9 C₃₂H₄₉N₇O₉ 
• 1367370-34-0 C₅₇H₈₆N₁₂O₁₄ 
• 39974-68-0 3,8-dioxa-1-azaspiro[4.5]decane-2,4-dione 

Relevant academic research and scientific papers

ALPHA, ALPHA - DI SUBSTITUTED GLYCINE ESTER DERIVATIVES AND THEIR USE AS HDAC INHIBITORS

Compounds selected from the following group and their salts are inhibitors of HDAC activity, useful in the treatment of, inter alia, cell proliferative disease and inflammation: Cyclopentyl 1 -[({5-[(1E)-3-(hydroxyamino)-3-oxoprop-1-en-1-yl]pyridin-2- yl}methy)amino]cyclopropanecarboxylate; Cyclopentyl 1 -[({5-[(1E)-3-(hydroxyamino)-3- oxoprop-1-en-1-yl]pyridin-2-yl}methy)amino]cyclobutanecarboxylate; Cyclopentyl 1-[({5- [(1E)-3-(hydroxyamino)-3-oxoprop-1-en-1-yl]pyridin-2yl}methyl)amino]- cyclopentanecarboxylate; Cyclopentyl 1-[({5-[(1E)-3-(hydroxyamino)-3-oxoprop-1-en-1- yl]pyridin-2-yl}methyl)amino]cyclohexanecarboxylate; Cyclopentyl 4-[({5-[(1E)-3- (hydroxyamino)-3-oxoprop-1 -en-1 -yl]pyridin-2-yl}methyl)amino]tetrahydro-2H-pyran-4- carboxylate; Cyclopentyl 4-[({6-[(1E)-3-{[1 -(2-methylpropoxy)ethoxy]amino}-3-oxoprop-1 - en-1 -yl]pyridin-3-yl}methyl)amino]tetrahydro-2H-pyran-4-carboxylate; Cyclopentyl 1 -({4- [(1E)-3-(hydroxyamino)-3-oxoprop-1-en-1-yl]-2-methylbenzyl}amino)- cyclohexanecarboxylate; Cyclopentyl 1-({4-[(1E)-3-(hydroxyamino)-3-oxoprop-1-en-1-yl]- 2-methylbenzyl}amino)cyclopentanecarboxylate; Cyclopentyl 1-({4-[(1E)-3- (hydroxyamino)-3-oxoprop-1-en-1-yl]-2-methylbenzyl}amino)cyclobutanecarboxylate; Methylcyclopentyl 4-[({6-[(1E)-3-(hydroxyamino)-3-oxoprop-1-en-1-yl]pyridin-3- yl}methyl)amino]tetrahydro-2H-pyran-4-carboxylate; Cyclopentyl 4-{[1 -({6-[(1E)-3- (hydroxyamino)-3-oxoprop-1-en-1-yl]pyridin-3-yl}methyl)piperidin-4-yl]amino}tetrahydro- 2H-pyran-4-carboxylate; Cyclopentyl 4-{[1-({5-[(1E)-3-(hydroxyamino)-3-oxoprop-1-en-1- yl]pyridin-2-yl}methyl)piperidin-4-yl]amino}tetrahydro-2H-pyran-4-carboxylate; Cyclopentyl 4-({4-[(1E)-3-(hydroxyamino)-3-oxoprop-1-en-1-yl]benzyl}amino)tetrahydro- 2H-pyran-4-carboxylate; Cyclopentyl 4-({3-[(1E)-3-(hydroxyamino)-3-oxoprop-1 -en-1 - yl]benzyl}amino)tetrahydro-2H-pyran-4-carboxylate; and (3R)-Tetrahydrofuran-3-yl N-{4- [(1E)-3-(hydroxyamino)-3-oxoprop-1-en-1-yl]benzyl}-2-methyl-D-leucinate.

Chemical communication: Conductors and insulators of screw-sense preference between helical oligo(aminoisobutyric acid) domains

1H NMR studies quantify the abilities of achiral amino acids to communicate a left-handed screw-sense preference from one helical Aib 4 domain to another: certain quaternary amino acids (e.g. Ac 6c) act as effective conductors of conformational preference while others (e.g. diphenylglycine) acts as insulators.

AMIDE STABILIZED HYDROXYETHYLAMINES

This invention pertains to amide and ester derivatives of hydroxyethylamine compounds that serve as effective beta-secretase inhibitors. The invention further relates to intermediates for preparation of such compounds; pharmaceutical compositions comprisi

N-SUBSTITUTED HETEROCYCLIC DERIVATIVES, THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS IN WHICH THEY ARE PRESENT

The invention relates to N-substituted heterocyclic derivatives and its salts. These derivatives have the formula (I) in which the substituents are as defined in the specification. Application: Angiotensin II antagonists