1384067-05-3

Basic information

• Product Name: 5-(3-fluorophenyl)-4-methylthiazol-2-amine
• Synonyms: 5-(3-fluorophenyl)-4-methylthiazol-2-amine
• CAS NO: 1384067-05-3
• Molecular Weight: 208.259
• Mol File: 1384067-05-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 5-(3-fluorophenyl)-4-methylthiazol-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(3-fluorophenyl)-4-methylthiazol-2-amine(1384067-05-3)
• EPA Substance Registry System: 5-(3-fluorophenyl)-4-methylthiazol-2-amine(1384067-05-3)

Safety Data

• Hazardous Substances Data: 1384067-05-3(Hazardous Substances Data)

Upstream product

• 1737-19-5 (3-fluorophenyl)acetone 
• 17356-08-0 thiourea 

Downstream Products

• 1384067-04-2 2-chloro-5-(3-fluorophenyl)-4-methylthiazole 

Relevant articles and documents

Efficient and facile strategy to substituted 2-aminothiazoles via ring opening of α-nitroepoxides

A novel and efficient reaction has been developed to synthesize a set of substituted 2-aminothiazoles from α-nitroepoxides and ammonium thiocyanate. This reaction could proceed smoothly at mild condition, to afford products for a wide range of substrates with good to excellent yields. A possible mechanism has also been proposed.

3,8-DIAZA-BICYCLO[4.2.0]OCT-8-YL AMIDES

The present invention relates to 3,8-diaza-bicyclo[4.2.0]oct-8-yl amide derivatives of formula (I) Formula (I) wherein the relative configuration of the diazabicyclooctane moiety is cis; and wherein Ar1, and Ar 2 are as described in the description, to their preparation, to pharmaceutically acceptable salts thereof, and to their use as pharmaceuticals, to pharmaceutical compositions containing one or more compounds of formula (I), and especially to their use as orexin receptor antagonists.