1384243-41-7Relevant academic research and scientific papers
Photochemistry of 2-Nitroarenes: 2-Nitrophenyl-α-trifluoromethyl Carbinols as Synthons for Fluoroorganics
Belligund, Kavita,Mathew, Thomas,Hunt, Jonathan R.,Nirmalchandar, Archith,Haiges, Ralf,Dawlaty, Jahan,Prakash, G. K. Surya
, p. 15921 - 15931 (2019)
Facile synthesis of a new series of 2,2′-bis(trifluoroacetyl) azoxybenzene derivatives and trifluoromethylated benzo[c]isoxazoline systems, along with trifluoroacetyl nitrosobenzene derivatives was achieved by solvent controlled photolysis of appropriate
Lithium binaphtholate-catalyzed enantioselective enyne addition to ketones: Access to enynylated tertiary alcohols
Cai, Hua,Nie, Jing,Zheng, Yan,Ma, Jun-An
, p. 5484 - 5493 (2014/07/08)
A new catalytic enantioselective enyne addition to ketones has been developed. In the presence of chiral lithium binaphtholate, the addition reaction proceeded smoothly to produce a series of enynylated tertiary alcohols in up to 96% yield and 94% enantiomeric excess. Convenient transformation of the adduct via Pauson-Khand cycloaddition reaction afforded the bicyclic product without detectable loss of enantioselectivity. Furthermore, catalytic asymmetric enyne addition to trifluoromethylketone was applied in the synthesis of the Efavirenz analogue.
