1384256-93-2Relevant academic research and scientific papers
SINGLET OXYGEN-LABILE LINKERS AND METHODS OF PRODUCTION AND USE THEREOF
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Paragraph 000177; 000179, (2013/11/18)
Activatable compositions that include at least one functional moiety and at least one cleavable linker directly or indirectly linked to the at least one functional moiety are disclosed. The at least one functional moiety is inactive when linked to the linker and activated upon cleavage of the linker. Methods of production and use of the activatable composition are also disclosed.
Click and photo-unclick chemistry of aminoacrylate for visible light-triggered drug release
Bio, Moses,Nkepang, Gregory,You, Youngjae
supporting information; experimental part, p. 6517 - 6519 (2012/07/28)
"Click and Photo-unclick Chemistry" of aminoacrylates is proposed for a new photo-labile linker. Adducts are built in 2 steps with good yields and cleaved rapidly by tissue penetrable visible light (690 nm) with a photosensitizer. Facile synthesis, release of mother drug, and stability and cleavage in medium are demonstrated.
