1384471-82-2Relevant academic research and scientific papers
Synthesis, characterization and their anticonvulsant, anti-inflammatory studies of some novel chromeno oxadiazoles
Ubaradka,Isloor, Arun M.,Shetty, Prakash,Shetty, Prashanth,Isloor, Nishitha A.
, p. 1497 - 1503 (2013/04/10)
In this study, a series of new 1,2,4-oxadiazole derivatives containing 3,4-dihydro-2H-chromen-2-amine moiety were synthesized by efficient microwave reaction of 2-amino-N′-hydroxychroman-3-carboxamidine and suitable aldehyde. Structures of all the synthesized compounds were confirmed by spectral studies and C, H, N analyses. Newly synthesized compounds were screened for their anticonvulsant and anti-inflammatory properties. Few of the compounds exhibited excellent anticonvulsant activity as compared to the standard drug Diazepam. Also compounds have exhibited moderate anti-inflammatory activity as compared to the standard drug Diclofenac sodium.
