1384487-73-3

Basic information

• Product Name: 15-methoxy-16a-phenyl-16,16a-dihydrobenzo[5,6][1,2,3]triazolo[5',1':3,4][1,4]diazepino[7,1-b]quinazolin-11(9H)-one
• Synonyms: 15-methoxy-16a-phenyl-16,16a-dihydrobenzo[5,6][1,2,3]triazolo[5',1':3,4][1,4]diazepino[7,1-b]quinazolin-11(9H)-one
• CAS NO: 1384487-73-3
• Molecular Weight: 409.447
• Mol File: 1384487-73-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 15-methoxy-16a-phenyl-16,16a-dihydrobenzo[5,6][1,2,3]triazolo[5',1':3,4][1,4]diazepino[7,1-b]quinazolin-11(9H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 15-methoxy-16a-phenyl-16,16a-dihydrobenzo[5,6][1,2,3]triazolo[5',1':3,4][1,4]diazepino[7,1-b]quinazolin-11(9H)-one(1384487-73-3)
• EPA Substance Registry System: 15-methoxy-16a-phenyl-16,16a-dihydrobenzo[5,6][1,2,3]triazolo[5',1':3,4][1,4]diazepino[7,1-b]quinazolin-11(9H)-one(1384487-73-3)

Safety Data

• Hazardous Substances Data: 1384487-73-3(Hazardous Substances Data)

Upstream product

• 2835-77-0 (2-aminophenyl)(phenyl)methanone 
• 3177-80-8 2-amino-3-methoxybenzoic acid 
• 16714-27-5 (2-azidophenyl)(phenyl)methanone 
• 1384487-61-9 2-amino-3-methoxy-N-(prop-2-yn-1-yl)benzamide 

Relevant articles and documents

One-pot, two-step cascade synthesis of quinazolinotriazolobenzodiazepines

An operationally simple, one-pot, two-step cascade method has been developed to afford quinazolino[1,2,3]triazolo[1,4]benzodiazepines. This unique, atom-economical transformation engages five reactive centers (amide, aniline, carbonyl, azide, and alkyne) and employs environmentally benign iodine as a catalyst. The method proceeds via sequential quinazolinone-forming condensation and intramolecular azide-alkyne 1,3-dipolar cycloaddition reactions. Substrate scope, multicomponent examples, and mechanistic insights are discussed.