1384525-54-5Relevant articles and documents
Synthesis of branched seven-membered 1-N-iminosugars and their evaluation as glycosidase inhibitors
Li, Hongqing,Zhang, Yongmin,Favre, Sylvain,Vogel, Pierre,Sollogoub, Matthieu,Bleriot, Yves
, p. 110 - 114 (2012/08/08)
Four branched tetra- and pentahydroxylated azepanes have been synthesized from a common azepane precursor through dihydroxylation followed by deoxygenation. They have been assayed as glycosidase inhibitors on a panel of 22 glycosidases and one methylated azepane displayed selective, competitive, and moderate inhibition toward bovine kidney α-l-fucosidase.