138467-90-0Relevant academic research and scientific papers
Electrochemical Reduction of Substituted Isothiazole-3-thiones in Aprotic Media
Martens, Thierry,Fleury, Maurice-Bernard
, p. 1763 - 1768 (2007/10/02)
The title compounds are obtained in good yields from 1,2-dithiole-3-thiones.Using cyclic voltammetry in dimethylformamide, two kinds of behaviour are evidenced and discussed in terms of the aromaticity of the 5-substituent (Ar).With Ar = pyrazinyl or pyridazinyl, isothiazole-3-thiones undergo an electrochemical chemical electrochemical mechanism and the rate constant of the chemical step has been deduced from voltammetric measurements.When the aromaticity increases (Ar = pyridyl or phenyl) an apparent one-step irreversible two-electron addition occurs.Whatever the nature of Ar the resulting two-electron reduction product has been isolated after controlled-potential electrolysis (CPE).In addition, in acetonitrile, CPE affords a thiophene derivative as a secondary product
