138471-15-5Relevant academic research and scientific papers
Reaction of 1-diethylaminopropyne with difunctionalized 4-nitroisoxazoles: A single step access to the Novel isoxazolo[4,5-c]isoxazole system
Nesi, Rodolfo,Giomi, Donatella,Papaleo, Sandro,Turchi, Stefania,Dapporto, Paolo,Paoli, Paola
, p. 6223 - 6226 (1991)
The nitroderivatives 1a-c were found to react with the title ynamine 2 under mild conditions to give the corresponding fused isoxazoles 3a-c, as proved by an X-ray diffraction of 3a; a plausible mechanistic pattern for these conversions is presented. Treatment of the nitroderivatives 1a-c with the ynamine 2 afforded the new bicyclic isoxazoles 3a-c as proved by an X-ray analysis of 3a.
