4231-35-0

Usage

Uses

Used in Organic Synthesis:
N,N-diethyl-1-propynylamine is utilized as a reagent and intermediate in organic synthesis, particularly for the production of pharmaceuticals and agrochemicals. Its unique chemical structure allows it to participate in a variety of reactions, facilitating the creation of complex organic molecules.
Used in Chemical Reactions as a Catalyst:
N,N-diethyl-1-propynylamine serves as a catalyst in numerous chemical reactions, enhancing the rate of these processes without being consumed in the reaction itself. Its catalytic properties are valuable in various industrial applications, contributing to more efficient production methods.
Used in Polymer Production as a Stabilizer:
N,N-diethyl-1-propynylamine is employed as a stabilizer in the production of polymers, helping to maintain the integrity and quality of the final polymer product. Its stabilizing effects are crucial in ensuring the durability and performance of polymers in different applications.
Used in Insect Repellent Formulations:
Recognized for its potential as an insect repellent, N,N-diethyl-1-propynylamine is being explored for its ability to deter insects, offering a possible alternative to traditional repellents for personal and environmental use.
Used in Research for Antimicrobial and Anti-Cancer Properties:
N,N-diethyl-1-propynylamine is under investigation for its potential antimicrobial and anti-cancer properties, with ongoing research aimed at understanding its mechanisms of action and potential applications in medicine.
Used in Various Industries:
N,N-diethyl-1-propynylamine is used across different industries, including pharmaceuticals, agrochemicals, polymer production, and research, for its diverse applications and contributions to the development of new products and processes.
Safety Note:
It is important to handle N,N-diethyl-1-propynylamine with care due to its highly flammable nature and potential to cause skin and respiratory irritation upon exposure. Proper safety measures should be implemented during its use to minimize risks.

InChI:InChI=1/C7H13N/c1-4-7-8(5-2)6-3/h5-6H2,1-3H3

Upstream product

• 4079-68-9 N,N-diethyl-2-propynylamine 
• 123-91-1 1,4-dioxane 
• 7440-69-9 bismuth 
• 109-89-7 diethylamine 
• 2430-00-4 2,2,2-trichloro-N,N-diethylacetamide 
• 686-10-2 N,N-diethyl-1,2,2-trichlorovinylamine 
• 74-88-4 methyl iodide 
• 80-48-8 methyl p-toluene sulfonate 

Downstream Products

• 61766-85-6 (5-ethoxy-4-methyl-1,1-dioxo-1H-1λ⁶-benzo[f][1,2]thiazepin-3-yl)-diethyl-amine 
• 61798-57-0 (1,1-dioxo-4-methyl-5-phenyl-1H-1λ⁶-benzo[f]thiazepin-3-yl)-diethyl-amine 
• 17234-06-9 4-((Z)-1-diethylamino-propylidene)-2-phenyl-4H-oxazol-5-one 
• 17136-80-0 2-Phenyl-4-methyl-4-(1-diethylamino-propen-(1)-yl)-oxazolon-(5) 
• 61766-86-7 (4-methyl-5-methylsulfanyl-1,1-dioxo-1H-1λ⁶-benzo[f][1,2]thiazepin-3-yl)-diethyl-amine 
• 71237-09-7 (3,5-dimethyl-1,4-diphenyl-1,4-dihydro-pyrano[2,3-c]pyrazol-6-yl)-diethyl-amine 
• 17136-82-2 4-benzyl-4-((Z)-1-diethylamino-propenyl)-2-phenyl-4H-oxazol-5-one 
• 71237-17-7 [3,5-dimethyl-4-(4-nitro-phenyl)-1-phenyl-1,4-dihydro-pyrano[2,3-c]pyrazol-6-yl]-diethyl-amine 
• 31004-35-0 Diethyl-[(E)-1-(N'-methyl-N-phenyl-hydrazino)-propenyl]-amine 
• 57221-07-5 diethyl-(5-methyl-2-p-tolyl-4,4-bis-trifluoromethyl-4H-[1,3]oxazin-6-yl)-amine 
• 21621-89-6 α-Methyl-γ.γ-diphenyl-allencarbonsaeure-diethylamid 
• 17691-86-0 3-(Diethylamino)-2-methyl-4,4-diphenyl-2-cyclobuten-1-on 
• 17115-26-3 3-Phenyl-3-benzoyloxy-methacrylsaeure-diethylamid 
• 66298-64-4 6-Diethylamino-5-methyl-2-phenyl-4,4-bis(trifluormethyl)-4H-1,3-thiazin 

Relevant academic research and scientific papers

Controlling Selectivity in the Synthesis of Z-α,β-Unsaturated Amidines by Tuning the N-Sulfonyl Group in a Rhodium(II) Catalyzed 1,2-H Shift

N2-Sulfonyl-α-diazo amidines can be synthesized by the reaction of electron rich alkynyl amines with electron poor sulfonyl azides through 1,3-dipolar cycloaddition that proceeds with perfect regioselectivity. In the presence of rhodium(II) carboxylate catalysts, denitrogenation occurs to give the corresponding metallocarbene but there are then two competing processes: 1,2–H shift and O-transfer from the sulfonyl group to the metallocarbene center. The outcome can be controlled using an electron poor nitrobenzenesulfonyl group and large carboxylate rhodium ligands to select for 1,2–H shift, forming α,β-unsaturated amidines in high yield and with excellent Z-selectivity.

PYRAZOLES USEFUL IN THE TREATMENT OF INFLAMMATION

There is provided compounds of formula (I), wherein R1, R2, X1, X2 and n have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of the activity of a lipoxygenase (e.g. 15-lipoxygenase) is desired and/or required, and particularly in the treatment of inflammation.

Preparation with heterogeneous catalysis of N-alkyl-substituted aminoalkynes

A process for preparing N-alkyl-substituted aminoalkynes by reacting an alkyne with a carbonyl compound and an amine with heterogeneous catalysis in which an unsupported copper acetylide derived from malachite is used as the catalyst. The N-alkyl-substituted aminoalkyne have a wide variety of uses including their use as precursors for pharmaceuticals, their use in electroplating processes and their use as corrosion inhibitors.

Base-catalysed isomerization of 2-propynylamines. Synthesis of (dialkylamino)allenes

A number of (dialkylamino)allenes 2 have been obtained in excellent yields and in a reasonable state of purity by isomerization of dialkyl-2-propynylamines 1 with potassium tert-butoxide in tetrahydrofuran or with the complex t-BuOK*t-BuOH in hexamethylphosphoric triamide.Treatment of the 2-propynylamines with t-BuOK in dimethyl sulfoxide leads to equilibrium mixtures of the allenic amines 2 and dialkyl-1-alkynylamines 3.