138476-68-3

Upstream product

• 82418-04-0 6-Oxo-10-ethyl-6,7,8,9-tetrahydro-pyrido<1,2-a>indol 
• 113140-81-1 5-methyl-1-(triphenylmethyl)-1H-imidazole-4-carboxaldehyde 

Downstream Products

• 129300-33-0 7-[(acetoxy)(5-methyl-1-trityl-1H-imidazol-4-yl)methyl]-10-ethyl-8,9-dihydropyrido[1,2-a]-indol-6(7H)-one 

Relevant academic research and scientific papers

New 5-HT3 (serotonin-3) receptor antagonists, I. Synthesis and structure-activity relationships of pyrido[1,2-a]indoles

A series of pyrido[1,2-a]indol-6(7H)-ones was prepared and evaluated for 5-HT3 receptor antagonist activity. The structural requirements for the 5-HT3 receptor antagonist have been defined as an aromatic moiety, a basic nitrogen, and

PYRIDOINDOLE DERIVATIVES AND PROCESSES FOR PREPARATION THEREOF

The invention relates to compounds for treatment of nausea and vomiting, of the formula STR1 wherein R 1 is hydrogen, lower alkyl, lower alkenyl or N,N-di(lower)alkylaminomethyl,R. sup.2 is hydrogen, lower alkyl or halogen,R 3 is imidazolyl or

Pyridoindole derivatives and processes for preparation thereof

Compounds of the formula: STR1 wherein R 1 is hydrogen, lower alkyl or lower alkenyl, R 2 is hydrogen, lower alkyl, or halogen, R 3 is imidazolyl or pyridyl, each of which may have suitable substituents, and R 4 is hydrogen, lower alkyl, lower alkenyl or