1384958-00-2

Upstream product

• 125923-35-5 methyl (N¹-benzyl-3-indolyl)acetate 
• 75-36-5 acetyl chloride 

Downstream Products

• 142605-15-0 (1R,1'R)-9-benzyl-2-(2-hydroxy-1-phenylethyl)-1-methyl-1,2,3,4-tetrahydropyrido<3,4-b>indole 
• 525-40-6 (R)-1-methyl-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole 
• 1374399-55-9 (R)-2-[(R)-2-hydroxy-1-phenylethyl]-1-methyl-1,2,3,4-tetrahydropyrido[3,4-b]indole 
• 1374399-83-3 (R)-9-benzyl-2-[(R)-2-hydroxy-1-phenylethyl]-1-methyl-3-oxo-1,2,3,4-tetrahydropyrido[3,4-b]indole 
• 1374399-76-4 2-acetyl-1-benzyl-3-indoleacetic acid 

Relevant academic research and scientific papers

Cyclocondensation reactions between 2-acyl-3-indoleacetic acid derivatives and phenylglycinol: Enantioselective synthesis of 1-substituted tetrahydro-β-carboline alkaloids

Cyclocondensation reactions between a variety of 2-acyl-3-indoleacetic acid derivatives and (R)-phenylglycinol were studied. Successful results were obtained from N-alkyl keto acid derivatives. The resulting tetracyclic lactams provide straightforward access to enantiopure 1-substituted tetrahydro-β- carboline alkaloids.