138498-84-7

Upstream product

• 67-56-1 methanol 
• 51359-78-5 4-(bromomethyl)benzaldehyde 

Downstream Products

• 250784-37-3 4-((1,2:3,4-di-O-isopropylidene-α-D-galactopyranos-6-oxy)methyl)benzaldehyde dimethyl acetal 
• 1221440-39-6 C₁₈H₂₇NO₄ 
• 1221440-37-4 C₁₇H₂₂N₂O₄ 
• 1221440-31-8 C₂₁H₂₅NO₄ 
• 1221440-41-0 C₁₈H₂₇NO₄ 
• 250784-41-9 4-(cholesteryloxymethyl)phenyl-bis(5-ethoxycarbonyl-4-ethyl-3-methyl-2-pyrryl)methane 
• 179678-42-3 4-(cholesteryloxymethyl)phenyl-bis(4-ethyl-3-methyl-2-pyrryl)methane 
• 250784-40-8 [4-((1,2:3,4-di-O-isopropylidene-α-D-galactopyranos-6-oxy)methyl)phenyl]-bis(5-ethoxycarbonyl-4-ethyl-3-methyl-2-pyrryl)methane 
• 179678-41-2 4-(1,2:3,4-di-O-isopropylidene-α-D-galactopyranos-6-oxymethyl)phenyl-bis(4-ethyl-3-methyl-2-pyrryl)methane 
• 250784-39-5 4-(cholesteryloxymethyl)benzaldehyde dimethyl acetal 

Relevant academic research and scientific papers

Dynamic combinatorial chemistry with hydrazones: Libraries incorporating heterocyclic and steroidal motifs

We expand the possibilities in hydrazone based dynamic combinatorial chemistry with a series of new building blocks incorporating heterocyclic motifs. The synthetic procedure allows efficient access to building blocks with the general structure (MeO)2CH-Heterocycle-C(O)NHNH2, originating from heterocycles with an amine and an ester functionality. The equilibrium distribution of macrocyclic N-acyl hydrazones formed upon deprotection of the building blocks with TFA in organic solvents is reported. The mixing behaviour of these heterocycle-based building blocks with our cholate-based building blocks is described, particularly the observation of kinetic intermediates that disappear following 'proof-reading'. The Royal Society of Chemistry.

HIV protease inhibitors useful for the treatment of aids

[From equivalent EP0434365A2] Compounds of the form, A-G-B-B-J wherein A is an amine protecting group or urethane, G a dipeptide isostere substituted with a basic amine nitrogen, B an amino acid or analog thereof, and J a small terminal group are describe