138505-09-6

Basic information

• Product Name: Butanamide, N-[2-(3-methoxyphenyl)ethyl]-
• CAS NO: 138505-09-6
• Molecular Formula: C13H19NO2
• Molecular Weight: 221.299
• Mol File: 138505-09-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Butanamide, N-[2-(3-methoxyphenyl)ethyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Butanamide, N-[2-(3-methoxyphenyl)ethyl]-(138505-09-6)
• EPA Substance Registry System: Butanamide, N-[2-(3-methoxyphenyl)ethyl]-(138505-09-6)

Safety Data

• Hazardous Substances Data: 138505-09-6(Hazardous Substances Data)

Upstream product

• 141-75-3 butyryl chloride 
• 2039-67-0 2-(3-methoxyphenyl)-1-ethanamine 
• 106-31-0 butanoic acid anhydride 
• 107-92-6 butyric acid 

Downstream Products

• 138505-00-7 2-(2-bromo-5-methoxybenzoyl)-1,2,3,4-tetrahydro-6-methoxy-1-propylidene-isoquinoline 

Relevant articles and documents

Synthesis of a small library of phenylalkylamide derivatives as melatoninergic ligands for human mt1 and MT2 receptors

Focused small libraries of melatonin receptor ligands from arylalkylamine derivatives were synthesised by combinatorial chemistry using the mix and split method in the solid phase. A library of 108 compounds was then synthesised from 12 arylalkyl amines and nine carboxylic acids. The compound mixtures were evaluated on chicken brain melatonin and recombinant human mt1 and MT2 receptors. Deconvolution of the most potent mixture demonstrated the superiority of 3-methoxy and 2,5-dimethoxy substitution on the phenyl ring with isopropyl, propyl and ethyl amido chains. Several compounds with nanomolar affinity for human melatonin receptors were obtained. (C) 2000 Elsevier Science Ltd.

Synthesis of C-13-alkylated 8-oxoberbines

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