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1385050-41-8

9-(2-chlorobenzyl)-6-(1H-1,2,4-triazol-1-yl)-9H-purine is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1385050-41-8 Structure

  • Basic information

    1. Product Name: 9-(2-chlorobenzyl)-6-(1H-1,2,4-triazol-1-yl)-9H-purine
    2. Synonyms: 9-(2-chlorobenzyl)-6-(1H-1,2,4-triazol-1-yl)-9H-purine
    3. CAS NO:1385050-41-8
    4. Molecular Formula:
    5. Molecular Weight: 311.733
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1385050-41-8.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 9-(2-chlorobenzyl)-6-(1H-1,2,4-triazol-1-yl)-9H-purine(CAS DataBase Reference)
    10. NIST Chemistry Reference: 9-(2-chlorobenzyl)-6-(1H-1,2,4-triazol-1-yl)-9H-purine(1385050-41-8)
    11. EPA Substance Registry System: 9-(2-chlorobenzyl)-6-(1H-1,2,4-triazol-1-yl)-9H-purine(1385050-41-8)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1385050-41-8(Hazardous Substances Data)

1385050-41-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1385050-41-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,8,5,0,5 and 0 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1385050-41:
(9*1)+(8*3)+(7*8)+(6*5)+(5*0)+(4*5)+(3*0)+(2*4)+(1*1)=148
148 % 10 = 8
So 1385050-41-8 is a valid CAS Registry Number.

1385050-41-8Downstream Products

1385050-41-8Relevant articles and documents

Synthesis of C6-azolyl purine nucleosides via C-N coupling reaction of unprotected 6-chloropurine nucleosides and N-heterocycles under catalyst- and solvent-free conditions

Qu, Gui-Rong,Zhang, Hong-Liang,Niu, Hong-Ying,Xue, Zai-Kun,Lv, Xin-Xin,Guo, Hai-Ming

, p. 1877 - 1879 (2012)

C6-azolyl purine nucleoside products are prepared in high yields under solvent- and catalyst-free conditions via C-N coupling reaction of unprotected 6-chloropurine nucleosides and N-heterocycles, providing a unifying, simple and environmentally friendly complement to the available methods. The Royal Society of Chemistry 2012.

Synthesis and anticonvulsant activity of novel purine derivatives

Wang, Shi-Ben,Jin, Peng,Li, Fu-Nan,Quan, Zhe-Shan

, p. 574 - 583 (2015/03/14)

A series of new purines containing triazole and other heterocycle substituents was synthesized and evaluated for their preliminary anticonvulsant activity and neurotoxicity by using the maximal electroshock (MES), subcutaneous pentylenetetrazole (scPTZ) and rotarod neurotoxicity (TOX) tests. Among the compounds studied, 9-decyl-6-(1H-1,2,4-triazol-1-yl)-9H-purine (5e) was the most potent compound, with a median effective dose of 23.4 mg/kg and a high protective index of more than 25.6 after intraperitoneal administration in mice. Compound 5e showed significant oral activity against MESinduced seizures in mice, with an ED50 of 39.4 mg/kg and a PI above 31.6. These results demonstrate that compound 5e possesses better anticonvulsant activity and is safer than the commercially available drugs carbamazepine and valproate in MES, scPTZ and TOX models.

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