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Pidobenzone is a pharmaceutical compound that is specifically designed for the treatment of Melasma, a condition characterized by acquired blotchy and odd patterned skin discoloration on the face and neck. It functions by targeting and reducing the appearance of these discolorations, providing a more even skin tone.

138506-45-3

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138506-45-3 Usage

Uses

Used in Pharmaceutical Industry:
Pidobenzone is used as a therapeutic agent for the treatment of Melasma. It is particularly effective in addressing the acquired blotchy and odd patterned skin discoloration on the face and neck, helping to improve the patient's overall skin appearance and quality of life.

Check Digit Verification of cas no

The CAS Registry Mumber 138506-45-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,8,5,0 and 6 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 138506-45:
(8*1)+(7*3)+(6*8)+(5*5)+(4*0)+(3*6)+(2*4)+(1*5)=133
133 % 10 = 3
So 138506-45-3 is a valid CAS Registry Number.
InChI:InChI=1/C11H11NO4/c13-7-1-3-8(4-2-7)16-11(15)9-5-6-10(14)12-9/h1-4,9,13H,5-6H2,(H,12,14)/t9-/m0/s1

138506-45-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name (4-hydroxyphenyl) (2S)-5-oxopyrrolidine-2-carboxylate

1.2 Other means of identification

Product number -
Other names Pidobenzone

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:138506-45-3 SDS

138506-45-3Downstream Products

138506-45-3Relevant academic research and scientific papers

Synthesis and bioactivities evaluation of L-pyroglutamic acid analogues from natural product lead

Gang, Fang-li,Zhu, Feng,Li, Xiao-ting,Wei, Jie-lu,Wu, Wen-jun,Zhang, Ji-wen

, p. 4644 - 4649 (2018)

A series of L-pyroglutamic acid analogues from natural product lead were designed and synthesized, as well as their antifungal activities against Phytophthora infestans, neuritogenic activities, antibacterial activities and anti-inflammatory activities are described. The bioassays and SAR study showed that the majority of L-pyroglutamic acid esters have a significant antifungal activity against P. infestans, especially 2d and 2j demonstrated the best activities with EC50 values of 1.44 and 1.21 μg mL?1, which were about seven times that of commercial azoxystrobin (7.85 μg mL?1). Moreover, compounds 2e, 2g and 4d displayed anti-inflammatory activity against LPS-induced NO production in BV-2 microglial cells; neuritogenic activity in NGF-induced PC-12 cells is the same activity. This study demonstrates that compounds 2d and 2j are potential drugs to control P. infestans.

Hydroquinone amino-acid esters, methods of preparation, and pharmaceutical or cosmetic compositions containing them

-

, (2008/06/13)

Hydroquinone amino-acid esters having formula (I), pharmaceutical or cosmetic compositions containing them, particularly dermatological compositions having pigment-removing activity, and the pharmaceutical, cosmetic or aesthetic uses thereof. The preparation of these novel hydroquinone esters from natural amino-acid derivatives is also described. STR1

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