138557-88-7

Basic information

• Product Name: 2,4(1H,3H)-Pyrimidinedione, 1,3-dimethyl-6-[4-[2-(4-nitrophenyl)ethyl]-1-piperazinyl]-
• CAS NO: 138557-88-7
• Molecular Formula: C18H23N5O4
• Molecular Weight: 373.412
• Mol File: 138557-88-7.mol

Chemical Properties

• CAS DataBase Reference: 2,4(1H,3H)-Pyrimidinedione, 1,3-dimethyl-6-[4-[2-(4-nitrophenyl)ethyl]-1-piperazinyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4(1H,3H)-Pyrimidinedione, 1,3-dimethyl-6-[4-[2-(4-nitrophenyl)ethyl]-1-piperazinyl]-(138557-88-7)
• EPA Substance Registry System: 2,4(1H,3H)-Pyrimidinedione, 1,3-dimethyl-6-[4-[2-(4-nitrophenyl)ethyl]-1-piperazinyl]-(138557-88-7)

Safety Data

• Hazardous Substances Data: 138557-88-7(Hazardous Substances Data)

Upstream product

• 5339-26-4 (4-nitrophenyl)ethyl bromide 
• 80210-72-6 1,3-dimethyl-6-(piperazine-1-yl)-2,4(1H,3H)-pyrimidinedione 

Relevant articles and documents

Pyrimidinedione derivatives and antiarrhythmic agents containing same

Pyrimidinedione derivatives of the formula: STR1 wherein R1 and R2 is so linked with each other as to make an alkylene chain and thus form a heterocyclic structure, A, R3, R4, X1, X2 and X3 are substituents, respectively, and n is 2 or 3 have a basic backbone in which a phenyl group part and a pyrimidinedione part are linked by a structure comprising an alkyl chain and a heterocyclic ring having two nitrogen atoms. These compounds are useful for a medical treatment of cardiac arrhythmias.

Synthesis and pharmacological studies of N-substituted 6-[(2- aminoethyl)amino]-1,3-dimethyl-2,4(1H,3H)-pyrimidinediones, novel class III antiarrhythmic agents

A series of 6-[(2-aminoethyl)amino]-1,3-dimethyl-2,4(1H,3H)- pyrimidinedione derivatives were synthesized and studied for their class III electrophysiological activity and class II (β-blocking) effects in in vitro and in vivo models. Structure-activity re

Pyrimidinedione compounds, method of producing the same and antiarrythmic agents containing the same

A pyrimidinedione derivative compound has a basic backbone in which a phenyl group part and a pyrimidinedione part are linked by a structure comprising an alkyl chain containing at least two nitrogen atoms. The pyrimidinedione derivative is useful for a medical treatment of cardiac arrhythmias.