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  • 138564-60-0 Structure
  • Basic information

    1. Product Name: 4-Amino-2-methyl-10H-thiene[2,3-b][1,5]benzodiazepine hydrochloride
    2. Synonyms: 4-Amino-2-methyl-10H-thienol[2.3-B][1.5] Benzodiazepine HCl;3-b][1;4-AMino-2-Methyl-10H-thieno[2;5] benzodiazapine HCl;4-AMino-2-Methyl-10H-thienol[2.3-B][1.5]benzodiazepine hydrochloride;2-Methyl-10H-thieno[2,3-b][1,5]benzodiazepin-4-aMine Hydrochloride;OlanzaMine;2-Methyl-10H-benzo[b]thieno[2,3-e][1,4]diazepin-4-aMine hydrochloride
    3. CAS NO:138564-60-0
    4. Molecular Formula: C12H12ClN3S
    5. Molecular Weight: 265.76
    6. EINECS: 1533716-785-6
    7. Product Categories: Heterocycles;Intermediates;Olanzapine;Amines;Chemical Amines;Aromatics
    8. Mol File: 138564-60-0.mol
    9. Article Data: 0
  • Chemical Properties

    1. Melting Point: 283-285°C
    2. Boiling Point: 459.8 °C at 760 mmHg
    3. Flash Point: 231.9 °C
    4. Appearance: Yellow crystaline solid
    5. Density: N/A
    6. Vapor Pressure: 0.000739mmHg at 25°C
    7. Refractive Index: N/A
    8. Storage Temp.: -20°C Freezer
    9. Solubility: DMSO (Slightly), Methanol (Sparingly, Sonicated)
    10. CAS DataBase Reference: 4-Amino-2-methyl-10H-thiene[2,3-b][1,5]benzodiazepine hydrochloride(CAS DataBase Reference)
    11. NIST Chemistry Reference: 4-Amino-2-methyl-10H-thiene[2,3-b][1,5]benzodiazepine hydrochloride(138564-60-0)
    12. EPA Substance Registry System: 4-Amino-2-methyl-10H-thiene[2,3-b][1,5]benzodiazepine hydrochloride(138564-60-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: 36/37/38
    3. Safety Statements: 26-36/37/39
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 138564-60-0(Hazardous Substances Data)

138564-60-0 Usage

Description

4-Amino-2-methyl-10H-thiene[2,3-b][1,5]benzodiazepine hydrochloride is an organic compound that serves as an intermediate in the synthesis of Olanzapine, a widely used antipsychotic medication. It is a yellow crystalline solid with unique chemical properties that make it a valuable component in the pharmaceutical industry.

Uses

Used in Pharmaceutical Industry:
4-Amino-2-methyl-10H-thiene[2,3-b][1,5]benzodiazepine hydrochloride is used as an intermediate in the preparation of Olanzapine (O253750) for its role in the synthesis of antipsychotic drugs. The compound plays a crucial part in the development of medications that help manage and treat various mental health disorders, such as schizophrenia and bipolar disorder.
As an intermediate, 4-Amino-2-methyl-10H-thiene[2,3-b][1,5]benzodiazepine hydrochloride contributes to the overall chemical structure of Olanzapine, which is known for its effectiveness in treating the symptoms of psychotic conditions. Its presence in the synthesis process is essential for the production of a drug that can provide relief and improve the quality of life for patients suffering from these disorders.

Check Digit Verification of cas no

The CAS Registry Mumber 138564-60-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,8,5,6 and 4 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 138564-60:
(8*1)+(7*3)+(6*8)+(5*5)+(4*6)+(3*4)+(2*6)+(1*0)=150
150 % 10 = 0
So 138564-60-0 is a valid CAS Registry Number.
InChI:InChI=1/C9H8N2.ClH/c1-2-6-9-8(4-1)5-3-7-10-11-9;/h1-7,11H;1H

138564-60-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-Amino-2-methyl-10H-thieno[2,3-b][1,5]-benzodiazapine, Hydrochloride

1.2 Other means of identification

Product number -
Other names 2-Methyl-10H-benzo[b]thieno[2,3-e][1,4]diazepin-4-amine hydrochloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:138564-60-0 SDS

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