1385768-77-3

Basic information

• Product Name: N-(biphenyl-4-yl)pent-4-enaMide
• Synonyms: N-(biphenyl-4-yl)pent-4-enaMide
• CAS NO: 1385768-77-3
• Molecular Formula: C17H17NO
• Molecular Weight: 251.32298
• Mol File: 1385768-77-3.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 447.8±34.0 °C(Predicted)
• Appearance: /
• Density: 1.081±0.06 g/cm3(Predicted)
• PKA: 14.70±0.70(Predicted)
• CAS DataBase Reference: N-(biphenyl-4-yl)pent-4-enaMide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(biphenyl-4-yl)pent-4-enaMide(1385768-77-3)
• EPA Substance Registry System: N-(biphenyl-4-yl)pent-4-enaMide(1385768-77-3)

Safety Data

• Hazardous Substances Data: 1385768-77-3(Hazardous Substances Data)

Upstream product

• 591-80-0 pent-4-enoic acid 
• 39716-58-0 pent-4-enoyl chloride 
• 92-67-1 4-phenylalanine 

Relevant articles and documents

Synthesis and biological evaluation of arylthiourea derivatives with antitubercular activity

Tuberculosis (TB) is a contagious disease caused by Mycobacterium tuberculosis (M. tuberculosis), and remains one of the most life-threatening plagues for public health in the world. The emergence of drug resistant strains of TB and co-infection with HIV has further complicated TB treatment. Here, the synthesis and characterizaton of a series of compounds were described, and these were followed by evaluating for their antibacterial activity against M. tuberculosis. Several novel arylthiourea derivatives exhibited excellent activity (lowest MIC=0.09 μg/ml) against M. tuberculosis including drug resistant strains of M. tuberculosis. The results suggest that these compounds are promising candidates for new anti-TB agent development.