13858-95-2Relevant academic research and scientific papers
Isoxazole biphenyl compound as well as preparation method and application thereof
-
Paragraph 0032-0033; 0034-0036; 0038; 0040-0042, (2021/10/11)
The invention relates to an isoxazole biphenyl compound and a preparation method and application thereof, and a structural formula of the isoxazole biphenyl compound. R1 Selected from the group consisting of or. R2 Selected from the
Hypervalent Iodine(III) Reagent Mediated Regioselective Cycloaddition of Aldoximes with Enaminones
Yoshimura, Akira,Jarvi, Melissa E.,Shea, Michael T.,Makitalo, Cody L.,Rohde, Gregory T.,Yusubov, Mekhman S.,Saito, Akio,Zhdankin, Viktor V.
, p. 6682 - 6689 (2019/11/02)
An efficient oxidative cycloaddition of enaminones with nitrile oxides generated in situ from respective aldoximes using hypervalent iodine reagents has been developed. Reactions of various aldoximes with enaminones in the presence of [hydroxy(tosyloxy)iodo]benzene involved the regioselective cycloaddition reaction resulting in the formation of the 3,4-disubstituted isoxazoles in moderate to good yields. Structures of several isoxazole products were confirmed by a single X-ray crystallography.
Aryl-isoxazol-4-yl-imidazole derivatives
-
Page/Page column 13, (2010/11/28)
The present invention is concerned with aryl-isoxazol-4-yl-imidazole derivatives of formula I: wherein R1 to R6 are as defmed in the specification and pharmaceutically acceptable acid addition salts thereof. This class of compounds h
Some Acylations of 3-Phenyl and 3-Mesityl-4,5-dihydroisoxazoles
Corsaro, Antonino,Chiacchio, Ugo,Perrini, Giancarlo,Caramella, Pierluigi,Albini, Franca Marinone
, p. 1691 - 1699 (2007/10/02)
A study on the acetylation and benzoylation of title compounds by quenching the corresponding 4-carbanions with acyl chlorides or esters is reported.The obtained ketones are formed as minor regioisomeric adducts in the cycloadditions of benzo and mesitoni
REACTION OF 1-DIALKYLAMINO(ALKOXY)-1-BUTEN-3-ONES WITH SOME 1,3-DIPOLAR SYSTEMS
Markova, N. K.,Tsil'ko, A. E.,Galishev, V. A.,Maretina, I. A.
, p. 1990 - 1993 (2007/10/02)
The corresponding functionally substituted isoxazoles, pyrazoles, and triazoles were obtained by the reaction of 1-dialkylamino-1-buten-3-ones and 1-alkoxy-1-buten-3-ones with benzonitrile N-oxide, acetyl- and ethoxycarbonyl-N-phenylnitrile imines, and p-
