138580-56-0Relevant academic research and scientific papers
Copper (II) chloride: A regioselective catalyst for oxidative aromatization of pyrazoline, isoxazoline and 3-methyl flavanones
Lokhande, Pradeep D.,Dalvi, Bhakti A.,Humne, Vivek T,Nawghare, Beena R.,Kareem, Abdul
, p. 1091 - 1097 (2014/09/30)
A new protocol has been reported in which a series of pyrazoline, isoxazoline and 3-methyl flavanone has been conveniently aromatized by using CuCl2.2H2O in DMSO within a short reaction time in excellent yields. The attraction of this new protocol is regioselective aromatization of substrate 3i-j and 5a-e which has been carried out to afford the aromatized product with O-allyl group intact in excellent yield.
PYRAZOLES AND ISOXAZOLES DERIVED FROM 2-HYDROXYARYL PHENYLETHYNYL KETONES: SYNTHESIS AND SPECTROPHOTOMETRIC EVALUATION OF THEIR POTENTIAL APPLICABILITY AS SUNSCREENS
Garcia, Heremengildo,Iborra, Sara,Miranda, Miguel A.,Morera, Isabel M.,Primo, Jaime
, p. 1745 - 1755 (2007/10/02)
Reaction of the acetylenic ketones (1) with hydrazine or hydroxylamine leads to the pyrazoles (2) or the isoxazoles (3), respectively.Spectrophotometric evaluation of the UV-photoprotecting ability as compared to p-aminobenzoic acid (PABA) shows that the predicted effectiveness of 2 and the 3-phenylisoxazoles (3B) is very close to that of PABA, while that of the 5-phenylisoxazoles (3A) is clearly lower.The pyrazoles (2) are more stable than PABA upon UV-irradiation in cyclohexane solution.
