138580-58-2Relevant academic research and scientific papers
β-cyclodextrin (β-CD) as a supramolecular catalyst for the synthesis of isoxazoles and thiopyrimidines and their antimicrobial screening
Chate, Asha V.,Gill, Charansingh H.
, p. 93 - 102 (2017/03/30)
Background: Isoxazole and pyrimidines are interesting heterocyclic molecules, which are present as structural motif in numerous natural products synthetic drugs. Isoxazole and thiopyrimidines exhibit antidiabetic, cytotoxic tuberculostatic, and anticonvul
PYRAZOLES AND ISOXAZOLES DERIVED FROM 2-HYDROXYARYL PHENYLETHYNYL KETONES: SYNTHESIS AND SPECTROPHOTOMETRIC EVALUATION OF THEIR POTENTIAL APPLICABILITY AS SUNSCREENS
Garcia, Heremengildo,Iborra, Sara,Miranda, Miguel A.,Morera, Isabel M.,Primo, Jaime
, p. 1745 - 1755 (2007/10/02)
Reaction of the acetylenic ketones (1) with hydrazine or hydroxylamine leads to the pyrazoles (2) or the isoxazoles (3), respectively.Spectrophotometric evaluation of the UV-photoprotecting ability as compared to p-aminobenzoic acid (PABA) shows that the predicted effectiveness of 2 and the 3-phenylisoxazoles (3B) is very close to that of PABA, while that of the 5-phenylisoxazoles (3A) is clearly lower.The pyrazoles (2) are more stable than PABA upon UV-irradiation in cyclohexane solution.
