104213-91-4Relevant articles and documents
Divergent Synthesis of Quinolones and Dihydroepindolidiones via Cu(I)-Catalyzed Cyclization of Anilines with Alkynes
Xu, Xuefeng,Sun, Ruzhong,Zhang, Sheng,Zhang, Xu,Yi, Wei
supporting information, p. 1893 - 1897 (2018/04/16)
A unique and efficient method for one-pot synthesis of diverse 4-quinolones from simple and readily available primary anilines and alkynes via Cu(I)-catalyzed direct cyclization has been developed. The (thio)phenols were also found to visible substrates for this reaction. Moreover, an unprecedented synthesis of dihydroepindolidiones has been demonstrated by using secondary anilines as the versatile substrates.
PHOTOLYSIS OF CYCLIC ACETALS OF ARYL BENZOYLACETATES AS THE KEY STEP IN A NEW SYNTHESIS OF FLAVONES
Garcia, Hermenegildo,Iborra, Sara,Miranda, Miguel A.,Primo, Jaime
, p. 2511 - 2517 (2007/10/02)
Although the yields found for the photo-Fries rearrangement of the aryl benzoylacetates 1 are poor, blocking of the carbonyl group, as in the related acetal derivatives 3, results in a substantial preparative improvement.Thus, the o-hydroxydibenzoylmethanes 2 are obtained from 1 with an average yield of 18percent, while the corresponding acetals 4 are obtained from 3 with an average yield of 58 percent.Compounds 4 are efficiently converted into flavones 8 by means of wet silica gel, through hydrolysis of the acetal moiety and subsequent cyclization of the resulting o-hydroxydibenzoylmethanes 2.
