1385837-63-7

Basic information

• Product Name: 2-(allyl(2-(benzylsulfonyl)pyrimidin-4-yl)amino)-N-cyclohexyl-2-phenylacetamide
• Synonyms: 2-(allyl(2-(benzylsulfonyl)pyrimidin-4-yl)amino)-N-cyclohexyl-2-phenylacetamide
• CAS NO: 1385837-63-7
• Molecular Weight: 504.653
• Mol File: 1385837-63-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(allyl(2-(benzylsulfonyl)pyrimidin-4-yl)amino)-N-cyclohexyl-2-phenylacetamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(allyl(2-(benzylsulfonyl)pyrimidin-4-yl)amino)-N-cyclohexyl-2-phenylacetamide(1385837-63-7)
• EPA Substance Registry System: 2-(allyl(2-(benzylsulfonyl)pyrimidin-4-yl)amino)-N-cyclohexyl-2-phenylacetamide(1385837-63-7)

Safety Data

• Hazardous Substances Data: 1385837-63-7(Hazardous Substances Data)

Upstream product

• 100-44-7 benzyl chloride 
• 100-52-7 benzaldehyde 
• 31167-21-2 2-(benzylthio)pyrimidin-4-ol 
• 931-53-3 Cyclohexyl isocyanide 
• 1373521-21-1 2-(allyl(2-(benzylthio)pyrimidin-4-yl)amino)-N-cyclohexyl-2-phenylacetamide 

Downstream Products

• 1373521-11-9 2-(allyl(2-morpholinopyrimidin-4-yl)amino)-N-cyclohexyl-2-phenylacetamide 
• 1373521-35-7 2-((2-(4-chlorobenzylamino)pyrimidin-4-yl)(allyl)amino)-N-cyclohexyl-2-phenylacetamide 

Relevant articles and documents

4-Aminopyrimidine libraries from the Ugi-Smiles reaction of thiouracil

The Ugi-Smiles reaction of S-benzyl thiouracil have been exploited in several three-step sequences for the preparation of aminopyrimidine libraries with high diversity. After the 4-component coupling, oxidation of the thioether to sulfone is followed by displacement of the latter by various carbon-centered nucleophiles (cyanide, malonate, boronic acids) or amines. The efficiency of the whole sequence was further demonstrated with one-pot procedures.