1386393-98-1Relevant articles and documents
Palladium-catalyzed 1,1-difunctionalization of ethylene
Saini, Vaneet,Sigman, Matthew S.
supporting information; experimental part, p. 11372 - 11375 (2012/08/29)
The 1,1-difunctionalization of ethylene, with aryl/vinyl/heteroaryl transmetalating agents and vinyl electrophiles, is reported. The reaction is high-yielding under a low pressure of ethylene, and regioselectivity is generally high for the 1,1-disubstituted product. The process is highlighted by the use of heteroaromatic cross-coupling reagents, which have not been competent reaction partners in previously reported efforts.