1386394-39-3

Upstream product

• 403-42-9 1-(4-fluorophenyl)ethanone 
• 1565-90-8 (2E)-1-(4-fluorophenyl)-3-(furan-2-yl)prop-2-en-1-one 
• 870680-36-7 3-(4-fluoro-phenyl)-5-furan-2-yl-4,5-dihydro-pyrazole-1-carbothioic acid amide 
• 105-36-2 ethyl bromoacetate 

Relevant academic research and scientific papers

Pyrazoline-containing (or furyl) thiophene thiazoline ketone derivatives of the structure and its preparation and use

The invention relates to thiazolinone derivatives comprising pyrazoline and thiophene (or furan) structures, and a preparation method and an application thereof. The derivatives are characterized in that the derivatives have a general formula presented as

Discovery and modification of sulfur-containing heterocyclic pyrazoline derivatives as potential novel class of β-ketoacyl-acyl carrier protein synthase III (FabH) inhibitors

A series of sulfur-containing heterocyclic pyrazoline derivatives (C1-C18; D1-D9) have been synthesized and purified (all are new except one) to screen for FabH inhibitory activity. Compound C14 showed the most potent biological activity against Escherich