138650-00-7

Basic information

• Product Name: (2S,3S)-3-hydroxy-2-methyl-3-(1-phenylsulfanylcyclopentyl)propyl-N-tosylamide
• Synonyms: (2S,3S)-3-hydroxy-2-methyl-3-(1-phenylsulfanylcyclopentyl)propyl-N-tosylamide
• CAS NO: 138650-00-7
• Molecular Weight: 419.609
• Mol File: 138650-00-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (2S,3S)-3-hydroxy-2-methyl-3-(1-phenylsulfanylcyclopentyl)propyl-N-tosylamide(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3S)-3-hydroxy-2-methyl-3-(1-phenylsulfanylcyclopentyl)propyl-N-tosylamide(138650-00-7)
• EPA Substance Registry System: (2S,3S)-3-hydroxy-2-methyl-3-(1-phenylsulfanylcyclopentyl)propyl-N-tosylamide(138650-00-7)

Safety Data

• Hazardous Substances Data: 138650-00-7(Hazardous Substances Data)

Upstream product

• 138649-96-4 (4S)-3-<(2S,3S)-3-hydroxy-2-methyl-1-oxo-3-(1-phenylsulfanylcyclopentyl)propyl>-4-phenylmethyl-1,3-oxazolidin-2-one 
• 115205-40-8 1-phenylsulfanylcyclopentane carboxaldehyde 
• 98-59-9 p-toluenesulfonyl chloride 
• 138649-99-7 (2S,3S)-3-hydroxy-2-methyl-3-(1-phenylsulfanylcyclopentyl)propylamine 

Downstream Products

• 138649-95-3 (3R,4R)-3-methyl-4-phenylsulfanyl-1-tosyl-1-azaspiro<4.4>nonane 

Relevant articles and documents

Asymmetric aldol reactions of achiral 2-phenylsulfanyl aldehydes with small- and medium-sized carbocyclic rings: the synthesis of homochiral spirocyclic lactones, pyrrolidines and tetrahydrofurans

Chiral boron enolates based on the 1,3-oxazolidin-2-one auxiliary react with achiral 1-phenylsulfanylcycloalkanecarbaldehydes in anti- and syn-selective aldol processes to give the corresponding aldol products with moderate to excellent levels of diastereo- and enantio-control.Stereospecific cyclisation via an asymmetric episulfonium (thiiranium) ion leads to optically pure spirocyclic compounds in high chemical yields.