138662-62-1Relevant articles and documents
Cobalt-mediated alkylation of (4R) and (4S)-3-acetoacetyl-4-benzyloxazolidin-2-ones. Preparation of enantiopure diphenylmethyl-, 9-fluorenyl-, and (1-adamantyl)glycines
Galvez, Nicanor,Moreno-Manas, Marcial,Vallribera, Adelina,Molins, Elies,Cabrero, Araceli
, p. 6197 - 6200 (2007/10/03)
The Co(II) complexes of (4R) and (4S)-3-acetoacetyl-4-benzyloxazolidin-2-ones are alkylated diastereoselectively with diphenylmethyl, 9-fluorenyl, and 1-adamantyl bromide. The resulting products are converted into enantiopure α-substituted glycines. Similar results are obtained by alkylation of the free acetoacetyloxazolidinones under Co(II)-catalysis.
Chiral synthesis of D- and L-3,3-diphenylalanine (DIP), unusual α-amino acids for peptides of biological interest
Chen,Beylin,Marlatt,Leja,Goel
, p. 3293 - 3296 (2007/10/02)
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