138716-22-0

Basic information

• Product Name: 1-[1,1'-BIPHENYL]-4-YL-3-(DIMETHYLAMINO)-2-PROPEN-1-ONE
• Synonyms: 1-[1,1'-BIPHENYL]-4-YL-3-(DIMETHYLAMINO)-2-PROPEN-1-ONE;1-[1,1'-Biphenyl]-4-yl-3-(dimethylammino)-2-propen-1-one;1-([1,1'-Biphenyl]-4-yl)-3-(diMethylaMino)prop-2-en-1-one;(2E)-1-biphenyl-4-yl-3-(dimethylamino)prop-2-en-1-one;(E)-1-([1,1'-biphenyl]-4-yl)-3-(dimethylamino)prop-2-en-1-one
• CAS NO: 138716-22-0
• Molecular Formula: C₁₇H₁₇NO
• Molecular Weight: 251.32
• Mol File: 138716-22-0.mol

Chemical Properties

• Melting Point: 134-136°C
• Boiling Point: 392.4°Cat760mmHg
• Flash Point: 146.9°C
• Appearance: /
• Density: 1.062g/cm³
• CAS DataBase Reference: 1-[1,1'-BIPHENYL]-4-YL-3-(DIMETHYLAMINO)-2-PROPEN-1-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[1,1'-BIPHENYL]-4-YL-3-(DIMETHYLAMINO)-2-PROPEN-1-ONE(138716-22-0)
• EPA Substance Registry System: 1-[1,1'-BIPHENYL]-4-YL-3-(DIMETHYLAMINO)-2-PROPEN-1-ONE(138716-22-0)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 138716-22-0(Hazardous Substances Data)

Usage

Uses

1-[1,1'-BIPHENYL]-4-YL-3-(DIMETHYLAMINO)-2-PROPEN-1-ONE is used as a chemical intermediate for the synthesis of various organic compounds and pharmaceuticals. Its unique structure, which includes a dimethylamino group and a propenone group, allows it to be a versatile building block in the development of new molecules with potential applications in different industries.
Used in Pharmaceutical Industry:
1-[1,1'-BIPHENYL]-4-YL-3-(DIMETHYLAMINO)-2-PROPEN-1-ONE is used as a key intermediate in the synthesis of drugs, particularly those targeting specific biological receptors or enzymes. Its structural features enable the creation of molecules with desired pharmacological properties, such as improved binding affinity, selectivity, and bioavailability.
Used in Chemical Research:
1-[1,1'-BIPHENYL]-4-YL-3-(DIMETHYLAMINO)-2-PROPEN-1-ONE is used as a research compound in the study of organic chemistry, particularly in the exploration of new reaction pathways and the development of novel synthetic methods. Its unique structure provides opportunities for investigating the reactivity and properties of various functional groups, as well as the influence of structural modifications on the overall chemical behavior.
Used in Material Science:
1-[1,1'-BIPHENYL]-4-YL-3-(DIMETHYLAMINO)-2-PROPEN-1-ONE is used as a component in the development of advanced materials, such as organic semiconductors, sensors, and catalysts. Its electronic properties and structural characteristics can be exploited to design materials with tailored properties for specific applications, including energy conversion, storage, and environmental sensing.

Upstream product

• 92-91-1 biphenyl-4-acetaldehyde 
• 68-12-2 N,N-dimethyl-formamide 
• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 

Downstream Products

• 1314412-18-4 7-(4-phenylphenyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione 
• 84864-17-5 5-(<1,1'-biphenyl>-4-yl)-isoxazole 
• 478064-94-7 [1,1'-biphenyl]-4-yl(4-methylquinolin-3-yl)methanone 
• 1087644-45-8 7-(biphen-4-yl)-1,2,4-triazolo[1,5-a]pyrimidine 
• 1448799-05-0 [1,1'-biphenyl]-4-yl(5-hydroxy-6-methoxybenzofuran-3-yl)methanone 
• 446276-22-8 3-([1,1'-biphenyl]-4-yl)-1H-pyrazole 
• 1263040-58-9 3-biphenyl-4-yl-1-phenyl-1H-pyrazole 
• 1257317-86-4 6-(biphenyl-4-yl)-3-cyanopyridine-2-(1H)-thione 

Relevant articles and documents

Synthesis and molecular docking studies of novel pyrimidine derivatives as potential antibacterial agents

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Rh(III)-Catalyzed Enaminone-Directed C-H Coupling with α-Diazo-α-phosphonoacetate for Reactivity Discovery: Fluoride-Mediated Dephosphonation for C-C Coupling Reactions

Rh(III)-catalyzed enaminone-directed C-H coupling with α-diazo-α-phosphonoacetate has been used for the identification of fluoride-mediated dephosphonation C-C coupling reactivity for the synthesis of 4-hydroxy-1-naphthoates. Intermolecular C-C coupling of α-phosphonoacetate and benzaldehyde for (E)-selective α,β-unsaturated ester synthesis has also been achieved.

A copper-catalyzed three component reaction of aryl acetylene, sulfonyl azide and enaminone to form iminolactone via 6π electrocyclization

We developed a copper-catalyzed three component reaction of aryl acetylene, enaminone and sulfonyl azide to construct iminolactone via a cascade process involving copper-catalyzed alkyne-azide cycloaddition (CuAAC), Michael addition of metalated ketenimin

Co(III)-Catalyzed Enaminone-Directed C-H Amidation for Quinolone Synthesis

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Pd-catalyzed site selective C-H acetoxylation of aryl/heteroaryl/thiophenyl tethered dihydroquinolinones

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3-Acyl-5-hydroxybenzofuran derivatives as potential anti-estrogen breast cancer agents: A combined experimental and theoretical investigation

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