84864-17-5

Upstream product

• 92-91-1 biphenyl-4-acetaldehyde 
• 138716-22-0 3-(dimethylamino)-1-(biphenyl-4-yl)-2-propen-1-one 
• 210885-00-0 3-([1,1'-biphenyl]-4-yl)prop-2-yn-1-ol 
• 84864-25-5 3-(<1,1'-biphenyl>-4-yl)-3-oxopropionaldehyde oxime 

Downstream Products

• 78443-35-3 3-(<1,1'-biphenyl>-4-yl)-3-oxopropionitrile 
• 84864-05-1 3-(Biphenyl-4-carbonyl)-4-hydroxy-pyrrole-2,5-dione 

Relevant academic research and scientific papers

Preparation method of isoxazole derivative

The invention relates to a preparation method of an isoxazole derivative, which comprises the following steps of mixing an propargyl alcohol derivative, a halogen source, an acid and a solvent, and heating to react; adding the hydroxylamine into the react

Harnessing Stereospecific Z-Enamides through Silver-Free Cp?Rh(III) Catalysis by Using Isoxazoles as Masked Electrophiles

The stereospecific synthesis of Z-enamides is described in this paper. For the first time, isoxazoles have been employed as electrophiles in C-H functionalization to afford thermodynamically less stable Z-enamides utilizing salicylaldehydes in an atom- and step-economic fashion. The stereochemistry of enamides might originate from the relative disposition of atoms present in isoxazole and the intramolecular hydrogen bonding. The reaction showed excellent scope as several structurally and electronically diverse salicylaldehydes and isoxazoles reacted efficiently.