1387526-41-1

Basic information

• Product Name: 2-(cinnamyloxy)-N,N-diallylethanamine oxalate
• Synonyms: 2-(cinnamyloxy)-N,N-diallylethanamine oxalate
• CAS NO: 1387526-41-1
• Molecular Weight: 347.411
• Mol File: 1387526-41-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(cinnamyloxy)-N,N-diallylethanamine oxalate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(cinnamyloxy)-N,N-diallylethanamine oxalate(1387526-41-1)
• EPA Substance Registry System: 2-(cinnamyloxy)-N,N-diallylethanamine oxalate(1387526-41-1)

Safety Data

• Hazardous Substances Data: 1387526-41-1(Hazardous Substances Data)

Upstream product

• 17719-79-8 (N,N-diallyl)-2-aminoethanol 
• 144-62-7 oxalic acid 
• 4392-24-9 3-bromo-1-phenyl-1-propenyl bromide 

Relevant articles and documents

Deconstructing 14-phenylpropyloxymetopon: Minimal requirements for binding to mu opioid receptors

A series of phenylpropyloxyethylamines and cinnamyloxyethylamines were synthesized as deconstructed analogs of 14-phenylpropyloxymetopon and analyzed for opioid receptor binding affinity. Using the Conformationally Sampled Pharmacophore modeling approach, we discovered a series of compounds lacking a tyrosine mimetic, historically considered essential for μ opioid binding. Based on the binding studies, we have identified the optimal analogs to be N-methyl-N-phenylpropyl-2-(3-phenylpropoxy)ethanamine, with 1520 nM, and 2-(cinnamyloxy)-N-methyl-N-phenethylethanamine with 1680 nM affinity for the μ opioid receptor. These partial opioid structure analogs will serve as the novel lead compounds for future optimization studies.