138760-46-0

Upstream product

• 138760-44-8 1L-(1,2,4/3,5)-1,2:3,4-di-O-cyclohexylidene-5-O-methylene-1,2,3,4,5-pentahydroxycyclohexanepentol 
• 134073-32-8 2L-(2,3,5/4,6)-2,3:4,5-di-O-cyclohexylidene-6-O-methyl-2,3,4,5,6-pentahydroxycyclohexanone 

Downstream Products

• 136861-99-9 (1S,2R,3S,4R,5R,6R)-2,3,4-tris(benzyloxy)-5-benzyloxymethyl-7-oxabicyclo<4.1.0>heptane 
• 148983-67-9 1L-(1,2,4,6/3,5)-3,4,5-tri-O-benzyl-6-benzyloxymethyl-1,2,3,4,5-cyclohexanepentol 
• 126661-83-4 cyclophellitol 

Relevant academic research and scientific papers

Synthesis of (-)-conduritol F, (+)-conduritol B, cyclophellitol from L- quebrachitol

The methyl ether of cyclitols with vicinal hydroxyl group was cleaved chemoselectively in preference to both cis-and trans-cyclohexylidene moieties by AlCl3-n-Bu4NI to afford parent alcohols in good yields. (-) Conduritol F was prepared from L-quebrachitol, an optically active cyclitol from the serum of rubber trees, in five steps by use of the demethylation reaction. The first chiral synthesis of (+)-conduritol B and the total synthesis of cyclophellitol, a novel β-glucosidase inhibitor, are described.