1387637-04-8

Basic information

• Product Name: C₁₇H₁₂ClF₂N₃OS
• CAS NO: 1387637-04-8
• Molecular Weight: 379.818
• Mol File: 1387637-04-8.mol

Chemical Properties

• CAS DataBase Reference: C₁₇H₁₂ClF₂N₃OS(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₇H₁₂ClF₂N₃OS(1387637-04-8)
• EPA Substance Registry System: C₁₇H₁₂ClF₂N₃OS(1387637-04-8)

Safety Data

• Hazardous Substances Data: 1387637-04-8(Hazardous Substances Data)

Upstream product

• 873-74-5 4-Aminobenzonitrile 
• 40465-45-0 p-cyanophenyl isocyanate 
• 1387636-91-0 C₁₄H₁₁F₂N₃OS 
• 534-07-6 1,3-Dichloroacetone 
• 1387636-88-5 C₁₄H₉F₂N₃O 

Downstream Products

• 1387637-10-6 C₂₁H₂₁F₂N₅OS 
• 1388265-74-4 C₃₄H₃₀F₅N₉O₄S 
• 1387637-16-2 C₂₅H₂₇F₂N₅O₃S 
• 1387637-22-0 C₂₃H₂₅F₂N₇O₂S 

Relevant articles and documents

Design, synthesis and antiproliferative activities of diaryl urea derivatives bearing N-acylhydrazone moiety

A new series of diaryl urea derivatives bearing N-acylhydrazone moiety were designed and synthesized. All the target compounds were evaluated for their antiproliferative activities against human leukemia cell line (HL-60), human lung adenocarcinoma epithelial cell line (A549) and human breast cancer cell line (MDA-MB-231) in vitro by standard MTT assay. The pharmacological results indicated that some compounds exhibited promising antitumor activities. Compound 1j showed the most potent antiproliferative activity against the tested three cell lines with IC50 values of 0.13 μmol/L, 0.7 μmol/L and 0.5 μmol/L, respectively.