138774-98-8 Usage
General Description
BOC-D-METyr(Bzl)-OH CHA is a chemical compound that is commonly used in organic synthesis and peptide engineering. It is comprised of a BOC-protected D-methionine residue with a benzyl group attached to the side chain. The BOC-protected form is commonly used to protect the amino group from unwanted reactions during synthesis, while the benzyl group can be easily removed to reveal the thiol functionality of the methionine residue for further modification. BOC-D-METYR(BZL)-OH CHA is often utilized in the production of peptide-based drugs, bioconjugates, and other biologically active molecules. Overall, BOC-D-METyr(Bzl)-OH CHA plays a crucial role in the development of new pharmaceuticals and biotechnology products.
Check Digit Verification of cas no
The CAS Registry Mumber 138774-98-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,8,7,7 and 4 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 138774-98:
(8*1)+(7*3)+(6*8)+(5*7)+(4*7)+(3*4)+(2*9)+(1*8)=178
178 % 10 = 8
So 138774-98-8 is a valid CAS Registry Number.
138774-98-8Relevant articles and documents
Synthesis of (9R,12S)- and (9S,12S)-cycloisodityrosine and their N-methyl derivatives
Boger, Dale L.,Zhou, Jiacheng,Borzilleri, Robert M.,Nukui, Seiji,Castle, Steven L.
, p. 2054 - 2069 (2007/10/03)
Full details of the synthesis of (9R,12S)- and (9S,12S)-cycloisodityrosine and their N-methyl derivatives are detailed based on an intramolecular nucleophilic aromatic substitution reaction for formation of the key biaryl ether with 14-membered ring macrocyclization. Their comparison with prior samples and the documentation of a facile C9 epimerization within the natural 9S series are described.
