178208-61-2

Basic information

• Product Name: BOC-N-ME-D-TYR-OH DCHA
• Synonyms: BOC-N-ME-D-TYR-OH DCHA;BOC-N-ME-D-TYROSINE DCHA;BOC-N-METHYL-D-TYROSINE DICYCLOHEXYLAMMONIUM SALT;BOC-D-METYR-OH DCHA;N-ALPHA-T-BUTOXYCARBONYL-N-METHYL-D-TYROSINE DICYCLOHEXYLAMMONIUM SALT;N-ALPHA-(T-BUTYLOXYCARBONYL)-N-ALPHA-METHYL-D-TYROSINE DICYCLOHEXYLAMINE;Boc-N-Me-D-Tyr-OH;N-[(1,1-Dimethylethoxy)carbonyl]-N-methyl-D-tyrosine
• CAS NO: 178208-61-2
• Molecular Formula: C₁₅H₂₁NO₅
• Molecular Weight: 476.65
• Mol File: 178208-61-2.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Storage Temp.: Store at RT.
• CAS DataBase Reference: BOC-N-ME-D-TYR-OH DCHA(CAS DataBase Reference)
• NIST Chemistry Reference: BOC-N-ME-D-TYR-OH DCHA(178208-61-2)
• EPA Substance Registry System: BOC-N-ME-D-TYR-OH DCHA(178208-61-2)

Safety Data

• Hazardous Substances Data: 178208-61-2(Hazardous Substances Data)

Upstream product

• 300408-88-2 (R)-3-(4-benzyloxyphenyl)-2-tert-butoxycarbonylamino-propionic acid benzyl ester 
• 63769-58-4 (R)-3-(4-benzyloxy-phenyl)-2-tert-butoxycarbonylamino-propionic acid 
• 138774-98-8 (R)-3-(4-Benzyloxy-phenyl)-2-(tert-butoxycarbonyl-methyl-amino)-propionic acid 

Downstream Products

• 178208-48-5 3-fluoro-4-nitro-N-[N-(tert-butyloxycarbonyl)-N-methyl-D-tyrosyl]-L-phenylalanine methyl ester 
• 178208-46-3 3-fluoro-4-nitro-N-[N-(tert-butyloxycarbonyl)-N-methyl-D-tyrosyl]-D-phenylalanine methyl ester 
• 178208-44-1 (R)-2-(tert-Butoxycarbonyl-methyl-amino)-3-(4-hydroxy-phenyl)-propionic acid pentafluorophenyl ester 

Relevant articles and documents

CONJUGATES OF CELL BINDING MOLECULES WITH CYTOTOXIC AGENTS

A conjugate of a potent cytotoxic agent with a cell-surface receptor binding molecule having a formula (I), wherein T, L, m, n, Y, R1, R2, R3, R4, R5, R6, R7, R8, Rsu

Synthesis of (9R,12S)- and (9S,12S)-cycloisodityrosine and their N-methyl derivatives

Full details of the synthesis of (9R,12S)- and (9S,12S)-cycloisodityrosine and their N-methyl derivatives are detailed based on an intramolecular nucleophilic aromatic substitution reaction for formation of the key biaryl ether with 14-membered ring macrocyclization. Their comparison with prior samples and the documentation of a facile C9 epimerization within the natural 9S series are described.