138801-63-5Relevant academic research and scientific papers
First Total Synthesis of a Natural Thapsane
Srikrishna, Adusumilli,Krishnan, Kathiresan
, p. 1693 - 1694 (1991)
A stereospecific first total synthesis of a natural thapsane 1, from the readily available cyclogeraniol 8, is described.
Stereospecific construction of multiple contiguous quaternary carbons. Total synthesis of (±)-cis, anti, cis-1,8,12,12-tetramethyl-4- oxatricyclo[6.4.0.02,6]dodecan-3-ol, a thapsane isolated from Thapsia villosa var minor
Srikrishna,Krishnan
, p. 7751 - 7755 (2007/10/02)
The details of the first total synthesis of a natural thapsane 1g containing three contiguous quaternary carbon atoms, starting from cyclogeraniol (9) is described. The Claisen rearrangement of 9 with methoxypropene in the presence of a catalytic amount o
