138801-62-4

Upstream product

• 116-11-0 2-Methoxypropene 
• 472-20-8 β-cyclogeraniol 

Downstream Products

• 138801-63-5 Ethyl 4-(1,3,3-trimethyl-2-methylenecyclohexyl)-3-oxobutanoate 
• 138801-64-6 Ethyl 4-(1,3,3-trimethyl-2-methylenecyclohexyl)-2-diazo-3-oxobutanoate 
• 1312108-86-3 C₁₇H₂₆O₂ 

Relevant academic research and scientific papers

Stereospecific construction of multiple contiguous quaternary carbons. Total synthesis of (±)-cis, anti, cis-1,8,12,12-tetramethyl-4- oxatricyclo[6.4.0.02,6]dodecan-3-ol, a thapsane isolated from Thapsia villosa var minor

The details of the first total synthesis of a natural thapsane 1g containing three contiguous quaternary carbon atoms, starting from cyclogeraniol (9) is described. The Claisen rearrangement of 9 with methoxypropene in the presence of a catalytic amount o

First Total Synthesis of a Natural Thapsane

A stereospecific first total synthesis of a natural thapsane 1, from the readily available cyclogeraniol 8, is described.