138831-29-5Relevant articles and documents
Cephem sulfones as inactivators of human leukocyte elastase. 5. 7α- Methoxy- and 7α-chloro-1,1-dioxocephem 4-ketones
Alpegiani,Bissolino,Corigli,Del Nero,Perrone,Rizzo,Sacchi,Cassinelli,Franceschi,Baici
, p. 4003 - 4019 (1994)
Studies on cephem sulfones as inhibitors of human leukocyte elastase (HLE) have been extended to the new class of cephem 4-ketones. tert-Butyl and phenyl ketones were prepared from 4-carboxycephem derivatives, at either the sulfide or sulfone oxidation le