1388654-77-0Relevant academic research and scientific papers
PROCESS FOR THE PREPARATION OF STATINS IN THE PRESENCE OF BASE
-
, (2013/11/19)
The present invention relates to a process for the preparation of statins by means of a Julia-Kocienski reaction between an aldehyde and a sulfone derivative in the presence of an alkaline metal alkoxy base. The resulting derivatives are suitable as building blocks for statin type compounds such as cerivastatin, fluvastatin, pitavastatin and rosuvastatin.
PROCESS FOR THE PREPARATION OF STATINS IN THE PRESENCE OF BASE
-
, (2012/08/07)
The present invention relates to a process for the preparation of statins by means of a Julia-Kocienski reaction between an aldehyde and a sulfone derivative in the presence of an alkaline metal alkoxy base. The resulting derivatives are suitable as building blocks for statin type compounds such as cerivastatin, fluvastatin, pitavastatin and rosuvastatin.
