138889-30-2Relevant academic research and scientific papers
Synthesis of an inositol-containing trisaccharide related to insulin signal transduction
Jaworek, Christine H.,Calias, Pericles,Iacobucci, Sarah,D'Alarcao, Marc
, p. 667 - 670 (2007/10/03)
A synthesis of D-mannosyl-(α1-4)-D-glucosaminyl-(α1-6)-D-myo-inositol- 1:2-cyclic phosphate (1) from D-xylose, D-mannose, and D-glucal is reported. Compound 1 constitutes the terminal structure of the PI-PLC-released VSG membrane anchor of Trypanosomes and is structurally related to the inositol phosphate glycan implicated as an insulin second messenger in higher organisms.
