138899-82-8

Basic information

• Product Name: (S)-2-((S)-4-tert-Butoxycarbonyl-4-{2-fluoro-4-[(4-hydroxy-2-methyl-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-butyrylamino)-pentanedioic acid di-tert-butyl ester
• Synonyms: (S)-2-((S)-4-tert-Butoxycarbonyl-4-{2-fluoro-4-[(4-hydroxy-2-methyl-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-butyrylamino)-pentanedioic acid di-tert-butyl ester
• CAS NO: 138899-82-8
• Molecular Weight: 791.917
• Mol File: 138899-82-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-2-((S)-4-tert-Butoxycarbonyl-4-{2-fluoro-4-[(4-hydroxy-2-methyl-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-butyrylamino)-pentanedioic acid di-tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-((S)-4-tert-Butoxycarbonyl-4-{2-fluoro-4-[(4-hydroxy-2-methyl-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-butyrylamino)-pentanedioic acid di-tert-butyl ester(138899-82-8)
• EPA Substance Registry System: (S)-2-((S)-4-tert-Butoxycarbonyl-4-{2-fluoro-4-[(4-hydroxy-2-methyl-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-butyrylamino)-pentanedioic acid di-tert-butyl ester(138899-82-8)

Safety Data

• Hazardous Substances Data: 138899-82-8(Hazardous Substances Data)

Upstream product

• 112887-67-9 (S)-2-{2-Fluoro-4-[(4-hydroxy-2-methyl-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid 
• 32719-56-5 tri-tert-butyl N--L-glutamate 
• 88063-78-9 L-γ-glutamyl-L-glutamic acid tris-t-butyl ester 
• 138899-80-6 2-Fluoro-4-[(4-hydroxy-2-methyl-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoic acid 

Downstream Products

• 138899-53-3 (S)-2-((S)-4-Carboxy-4-{2-fluoro-4-[(4-hydroxy-2-methyl-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-butyrylamino)-pentanedioic acid; compound with trifluoro-acetic acid 

Relevant articles and documents

Syntheses and Thymidylate Synthase Inhibitory Activity of the Poly-γ-glutamyl Conjugates of N--2-thenoyl>-L-glutamic Acid (ICI D1694) and Other Quinazoline Antifolates

Thirteen poly-γ-glutamates derived from several novel antifolates have been synthesized by a convergent route.The syntheses of poly-γ-glutamyl conjugates of N--2-thenoyl>-L-glutamic aci