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CAS

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138900-26-2

1H-Indole-5-carbonitrile, 1-(4-fluorophenyl)-3-[1,2,3,6-tetrahydro-1-[2-(2-oxo-1-imidazolidinyl)eth yl]-4-pyridinyl]- is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1H-Indole-5-carbonitrile, 1-(4-fluorophenyl)-3-[1,2,3,6-tetrahydro-1-[2-(2-oxo-1-imidazolidinyl)ethyl]-4-pyridinyl]-

    Cas No: 138900-26-2

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  • 138900-26-2 Structure

  • Basic information

    1. Product Name: 1H-Indole-5-carbonitrile, 1-(4-fluorophenyl)-3-[1,2,3,6-tetrahydro-1-[2-(2-oxo-1-imidazolidinyl)eth yl]-4-pyridinyl]-
    2. Synonyms:
    3. CAS NO:138900-26-2
    4. Molecular Formula: C25H24FN5O
    5. Molecular Weight: 429.497
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 138900-26-2.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 1H-Indole-5-carbonitrile, 1-(4-fluorophenyl)-3-[1,2,3,6-tetrahydro-1-[2-(2-oxo-1-imidazolidinyl)eth yl]-4-pyridinyl]-(CAS DataBase Reference)
    10. NIST Chemistry Reference: 1H-Indole-5-carbonitrile, 1-(4-fluorophenyl)-3-[1,2,3,6-tetrahydro-1-[2-(2-oxo-1-imidazolidinyl)eth yl]-4-pyridinyl]-(138900-26-2)
    11. EPA Substance Registry System: 1H-Indole-5-carbonitrile, 1-(4-fluorophenyl)-3-[1,2,3,6-tetrahydro-1-[2-(2-oxo-1-imidazolidinyl)eth yl]-4-pyridinyl]-(138900-26-2)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 138900-26-2(Hazardous Substances Data)

138900-26-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 138900-26-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,8,9,0 and 0 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 138900-26:
(8*1)+(7*3)+(6*8)+(5*9)+(4*0)+(3*0)+(2*2)+(1*6)=132
132 % 10 = 2
So 138900-26-2 is a valid CAS Registry Number.

138900-26-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(2-{4-[5-cyano-1-(4-fluorophenyl)-1H-indol-3-yl]-1,2,3,6-tetrahydropyridin-1-yl}ethyl)-2-imidazolidinone

1.2 Other means of identification

Product number -
Other names 1-(4-Fluoro-phenyl)-3-{1-[2-(2-oxo-imidazolidin-1-yl)-ethyl]-1,2,3,6-tetrahydro-pyridin-4-yl}-1H-indole-5-carbonitrile

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
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More Details:138900-26-2 SDS

138900-26-2Relevant articles and documents

Noncataleptogenic, centrally acting dopamine D-2 and serotonin 5-HT2 antagonists within a series of 3-substituted 1-(4-fluorophenyl)-1H-indoles

Perregaard,Arnt,Bogeso,Hyttel,Sanchez

, p. 1092 - 1101 (2007/10/02)

A series of 1-(4-fluorophenyl)-1H-indoles substituted at the 3-position with 1-piperazinyl, 1,2,3,6-tetrahydro-4-pyridinyl, and 4-piperidinyl was synthesized. Within all three subseries potent dopamine D-2 and serotonin 5- HT2 receptor affinity was found in ligand binding studies. Quipazine-induced head twitches in rats were inhibited by most derivatives as a measure of central 5-HT2 receptor antagonism. Piperazinyl and tetrahydropyridyl indoles were cataleptogenic, while piperidyl substituted indoles surprisingly were found to be noncataleptogenic or only weakly cataleptogenic. Noncataleptogenic piperidyl derivatives also failed to block dopaminergic- mediated stereotypies, that is methyl phenidate-induced gnawing behavior in mice. These profiles resemble that of the atypical neuroleptic clozapine. 1- Ethyl-2-imidazolidinone was found to be the optimal substituent of the basic nitrogen atom in order to avoid catalepsy. The atypical neuroleptic 1-[2-[4- [5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl]-1-piperidinyl]ethyl]-2- imidazolidinone (sertindole, compound 14c) was selected for further development as a result of these structure/activity studies.

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