138904-87-7

Upstream product

• 95-14-7 1,2,3-Benzotriazole 
• 100-52-7 benzaldehyde 
• 108-98-5 thiophenol 

Downstream Products

• 138904-89-9 1-(1-Phenyl-1-phenylsulfanyl-pentyl)-1H-benzotriazole 
• 16928-67-9 4-methoxy-1-<α-(phenylthio)benzyl>benzene 
• 16222-09-6 1,2-diphenyl-2-(phenylthio)ethanone 
• 32121-59-8 α-(phenylthio)-benzyl cyanide 
• 74408-96-1 1,3-diphenyl-3-phenylsulfanyl-propan-1-one 
• 31488-60-5 3-(3,4-methylenedioxyphenyl)-1-phenyl-3-phenylsulphanylpropan-1-one 
• 21213-27-4 phenyl 1-phenyl-3-butenyl sulfide 
• 203070-16-0 1-(Phenyl-phenylselanyl-phenylsulfanyl-methyl)-1H-benzotriazole 
• 7695-69-4 bis(phenylthio)methylbenzene 

Relevant academic research and scientific papers

Oxidation of 1-[(Aryl)(phenylseleno)methyl]-, 1-[(Aryl)(arylthio)-(phenylseleno)methyl]-, and 1-[(Aryl)(diphenylseleno)-methyl]benzotriazoles with m-Chloroperbenzoic Acid

During the last decade, benzotriazole (1) has received much attention as an excellent synthetic auxiliary [1]. Recently Katritzky, et al. [2] studied the oxidation of 1-(phenylthiomethyl)benzotriazole (2a) and 1-(2-phenyl-1-phenylthioethyl)benzotriazole (2b) and obtained their sulfones and sulfoxides by treatment with m-chloroperbenzoic acid (m-CPBA) and sodium periodate, respectively. No compounds derived from a heterolytic cleavage between the α-carbon and the N-1 atoms of the foregoing compounds were isolated.

Thioalkylation of reactive aromatic compounds with α-(benzotriazol-1-yl)benzyl phenyl sulfide

1-[α-(Phenylthio)benzyl]- and 1[(4-methylphenyl)(phenylthio)methyl]benzotriazole, readily available from benzotriazole, an aldehyde and thiophenol, react with a variety of active aromatic compounds under mild conditions to give the thioalkylation products in moderate to good yields.

Efficient syntheses of thiochromans via cationic cycloadditions

α-(Benzotriazolyl)methyl thioethers 1a-e reacted with styrenes under Lewis acid catalysis to give novel polysubstituted thiochromans (3,4-dihydro-2H-1 -benzothiopyrans) 3-14 and 16-20 in generally high yields. Most thiochromans were isolated as one diastereomer following recrystallization. The configuration and conformation of the products are predicted on the basis of their NMR data. A stepwise reaction, proceeding via a [4+ + 2] cationic polar cycloaddition mechanism, is proposed.

A convenient route to β-phenylthioalkyl ketones

The preparation of β-phenylthioalkyl ketones via the reactions of α- benzotriazolylalkyl phenyl sulfides (1a-e) with enamines (5a-d) is described.

182. A Convenient Synthesis of Vinyl Sulfides

tert-Alkyl sulfides, with an α-(1H-benzotriazol-1-yl) group 6 and 13, are readily prepared from N--1H-benzotriazoles 3 and N-(11), respectively, by reaction with BuLi and then with the appropriate electrophile.The tert-alkyl sulfides 6 a