138907-85-4

Basic information

• Product Name: 1-(4-bromophenyl)-1H-pyrazole-4-carboxylic acid
• Synonyms: 1-(4-bromophenyl)-1H-pyrazole-4-carboxylic acid
• CAS NO: 138907-85-4
• Molecular Formula: C₁₀H₇BrN₂O₂
• Molecular Weight: 267.09
• Mol File: 138907-85-4.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(4-bromophenyl)-1H-pyrazole-4-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-bromophenyl)-1H-pyrazole-4-carboxylic acid(138907-85-4)
• EPA Substance Registry System: 1-(4-bromophenyl)-1H-pyrazole-4-carboxylic acid(138907-85-4)

Safety Data

• Hazardous Substances Data: 138907-85-4(Hazardous Substances Data)

Usage

General Description

1-(4-bromophenyl)-1H-pyrazole-4-carboxylic acid is a chemical compound that belongs to the class of pyrazole carboxylic acids. It is represented by the chemical formula C10H7BrN2O2 and has a molecular weight of 272.077 g/mol. 1-(4-bromophenyl)-1H-pyrazole-4-carboxylic acid is a derivative of pyrazole, which is a five-membered aromatic ring with two nitrogen atoms at positions 1 and 2. The presence of the carboxylic acid group makes it a potential building block for the synthesis of various organic compounds. The 4-bromophenyl group in the molecule provides it with certain reactivity and properties that can be utilized in various chemical reactions and applications. Overall, 1-(4-bromophenyl)-1H-pyrazole-4-carboxylic acid has the potential to be used in pharmaceutical, agricultural, and material science applications.

Upstream product

• 138907-76-3 ethyl 1-(4-bromophenyl)-1H-pyrazole-4-carboxylate 
• 138907-71-8 ethyl 5-amino-1-(4-bromophenyl)-1H-pyrazole-4-carboxylate 
• 622-88-8 4-bromophenylhydrazine hydrochloride 
• 294877-41-1 1-(4-bromophenyl)-1H-pyrazole-4-carboxyaldehyde 

Downstream Products

• 884851-01-8 1-(4-bromo-phenyl)-1H-pyrazole-4-carboxylic acid hydrazide 
• 884850-98-0 methyl 1-(4-bromophenyl)-1H-pyrazole-4-carboxylate 

Relevant articles and documents

Synthesis and oxidation of all isomeric 2-(pyrazolyl)ethanols

[Figure not available: see fulltext.] An efficient approach to the preparation of N-substituted 2-(pyrazol-4-yl)ethanols based on recyclization reaction of 3-(dimethoxymethyl)-2-methoxytetrahydrofuran with hydrazines is described. Oxidation by KMnO4 led to 2-(pyrazol-4-yl)-2-oxoacetic acids. In contrast, 2-(pyrazol-5-yl)ethanol under similar conditions gave only pyrazole-5-carboxylic acid, which formed as a result of oxidation followed by decarbonylation. 2-(Pyrazol-3-yl)ethanol in this oxidation reaction gave a mixture of 2-oxo-2-(pyrazol-3-yl)acetic acid and pyrazole-3-carboxylic acid.

Synthesis and leishmanicidal activities of 1-(4-X-phenyl)-N′-[(4-Y- phenyl)methylene]-1H-pyrazole-4-carbohydrazides

1H-pyrazole-4-carbohydrazides were synthesized and their leishmanicidal in vitro activities and cytotoxic effects were investigated. The drugs prototypes of these new compounds (ketoconazole, benznidazole, allopurinol and pentamidine) were also tested. It