138907-85-4

Usage

Uses

Used in Pharmaceutical Applications:
1-(4-bromophenyl)-1H-pyrazole-4-carboxylic acid is used as a building block for the synthesis of various pharmaceutical compounds due to its unique chemical structure and reactivity. The presence of the carboxylic acid group allows for the formation of esters, amides, and other derivatives, which can be further modified to create new drugs with specific therapeutic properties.
Used in Agricultural Applications:
In the agricultural industry, 1-(4-bromophenyl)-1H-pyrazole-4-carboxylic acid is used as a starting material for the development of new agrochemicals, such as pesticides and herbicides. Its reactivity and properties can be exploited to create compounds with improved efficacy and selectivity, leading to more effective and environmentally friendly products.
Used in Material Science Applications:
1-(4-bromophenyl)-1H-pyrazole-4-carboxylic acid is used as a key component in the development of advanced materials for various applications, such as electronics, optics, and coatings. Its unique chemical structure and properties can be utilized to create materials with enhanced performance characteristics, such as improved conductivity, stability, or durability.

Upstream product

• 294877-41-1 1-(4-bromophenyl)-1H-pyrazole-4-carboxyaldehyde 
• 622-88-8 4-bromophenylhydrazine hydrochloride 
• 138907-71-8 ethyl 5-amino-1-(4-bromophenyl)-1H-pyrazole-4-carboxylate 
• 138907-76-3 ethyl 1-(4-bromophenyl)-1H-pyrazole-4-carboxylate 

Downstream Products

• 884851-01-8 1-(4-bromo-phenyl)-1H-pyrazole-4-carboxylic acid hydrazide 
• 884850-98-0 methyl 1-(4-bromophenyl)-1H-pyrazole-4-carboxylate 

Relevant academic research and scientific papers

Synthesis and oxidation of all isomeric 2-(pyrazolyl)ethanols

[Figure not available: see fulltext.] An efficient approach to the preparation of N-substituted 2-(pyrazol-4-yl)ethanols based on recyclization reaction of 3-(dimethoxymethyl)-2-methoxytetrahydrofuran with hydrazines is described. Oxidation by KMnO4 led to 2-(pyrazol-4-yl)-2-oxoacetic acids. In contrast, 2-(pyrazol-5-yl)ethanol under similar conditions gave only pyrazole-5-carboxylic acid, which formed as a result of oxidation followed by decarbonylation. 2-(Pyrazol-3-yl)ethanol in this oxidation reaction gave a mixture of 2-oxo-2-(pyrazol-3-yl)acetic acid and pyrazole-3-carboxylic acid.

Synthesis of pyrazole-carboxamides and pyrazole-carboxylic acids derivatives: Simple methods to access powerful building blocks

Hybrid systems containing pyrazole moiety show a wide spectrum of biological activities. To access novel hybrids with pyrazole ring, in this work we synthesized twenty pyrazole-carboxylic acids and twenty pyrazole-carboxamides, using simple synthetic methods, to be used as building blocks in the development of new structures.

Synthesis and leishmanicidal activities of 1-(4-X-phenyl)-N′-[(4-Y- phenyl)methylene]-1H-pyrazole-4-carbohydrazides

1H-pyrazole-4-carbohydrazides were synthesized and their leishmanicidal in vitro activities and cytotoxic effects were investigated. The drugs prototypes of these new compounds (ketoconazole, benznidazole, allopurinol and pentamidine) were also tested. It