138908-48-2

Basic information

• Product Name: Benzenemethanol, 3-chloro-a-[[[2-(3,4-dimethoxyphenyl)-1-methylethyl]amino]methyl]-
• CAS NO: 138908-48-2
• Molecular Formula: C19H24ClNO3
• Molecular Weight: 349.857
• Mol File: 138908-48-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Benzenemethanol, 3-chloro-a-[[[2-(3,4-dimethoxyphenyl)-1-methylethyl]amino]methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanol, 3-chloro-a-[[[2-(3,4-dimethoxyphenyl)-1-methylethyl]amino]methyl]-(138908-48-2)
• EPA Substance Registry System: Benzenemethanol, 3-chloro-a-[[[2-(3,4-dimethoxyphenyl)-1-methylethyl]amino]methyl]-(138908-48-2)

Safety Data

• Hazardous Substances Data: 138908-48-2(Hazardous Substances Data)

Upstream product

• 161121-01-3 (S)-[2-(3,4-dimethoxyphenyl) 1-methylethyl methanesulfonate] 
• 111-92-2 dibutylamine 
• 121652-86-6 (R)-2-(3-Chlorophenyl)-2-hydroxyethylamine 
• 20697-04-5 3-chlorostyrene oxide 
• 13435-12-6 N-Trimethylsilylacetamide 
• 776-99-8 3,4-dimethoxyphenylacetone 
• 53360-89-7 2-amino-1-(3-chloro-phenyl)-ethanol 
• 161121-00-2 (S)-[2(3,4-dimethoxyphenyl)-1-methylethyl p-toluenesulfonate] 

Relevant articles and documents

Optically active 1-phenyl-2-substituted propane derivatives and methods of producing the same

An (S)-1-phenyl-2-substituted propane derivative shown by the following formula (I) STR1 wherein R1 and R2 represent a lower alkyl group, etc., or R1 and R2 may form together an alkylene group, etc.; R3, R4 and R5 represent a hydrogen atom, etc.; and X represents a hydroxyl group which may be protected with a protective group, or a halogen atom etc., can readily be produced (i) by permitting a microorganism belonging to the genus Torulaspora, the genus Candida, the genus Pichia or the like to act on a phenylacetone derivative and asymmetrically reducing the compound, or (ii) by sterically inverting an (R)-enantiomer. (R,R)-1-phenyl-2-[(2-phenyl-1-methylethyl)amino]ethanol derivative having a high optical purity can easily be obtained from the compound of the formula (I). The ethanol derivative is useful as an anti-obesity agent and the like.

Substituted 5-(2-((2-aryl-2-hydroxyethyl)amino)propyl)-1,3-benzodioxoles

The present invention discloses substituted 1,3-benzodioxoles which possess anti-diabetic and/or anti-hyperglycemic and/or anti-obesity properties in humans and other animals.