138944-03-3Relevant academic research and scientific papers
Addition of acrylamide to amino aldehydes to generate non-Baylis-Hillman adducts. Formation of novel N-acylhemiaminals
Bussolari, Jacqueline C.,Beers, Kimberly,Lalan, Praful,Murray, William V.,Gauthier, Diane,McDonnell, Patricia
, p. 787 - 788 (1998)
Aldol reactions of chiral aminoaldehydes and methylacrylate in the presence of 1,4-diazabicyclo[2.2.2]octane (DABCO) produces β-hydroxy methylbutenoates which can be utilized as psuedodipepetides. However, reaction of aminoaldehydes with acrylamide in the
Stereoselective addition of methyl acrylate to α-amino aldehydes
Manickum,Roos
, p. 2269 - 2274 (2007/10/02)
Variously N-protected α-aminoaldehydes exhibit reasonable diastereoselectivity in the Baylis-Hillman coupling with methyl acrylate to provide either primarily syn or anti α-methylene-β-hydroxy-γ-amino esters.
